[HTML][HTML] Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images

…, UK Biobank Eye and Vision Consortium… - PLoS …, 2021 - journals.plos.org
Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is
used to diagnose and manage ophthalmic diseases including glaucoma. We present the …

Associations of retinal microvascular diameters and tortuosity with blood pressure and arterial stiffness: United Kingdom Biobank

…, UK Biobank Eye and Vision Consortium - …, 2019 - Am Heart Assoc
To examine the baseline associations of retinal vessel morphometry with blood pressure
(BP) and arterial stiffness in United Kingdom Biobank. The United Kingdom Biobank …

[HTML][HTML] Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci

…, UK Biobank Eye and Vision Consortium - Human Genetics, 2018 - Springer
Previous studies have suggested that naturally occurring genetic variation contributes to the
risk of astigmatism. The purpose of this investigation was to identify genetic markers …

[HTML][HTML] Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

…, UK Biobank Eye and Vision Consortium - Nature …, 2023 - nature.com
Glaucoma is a progressive optic neuropathy and a leading cause of irreversible blindness
worldwide. Primary open-angle glaucoma is the most common form, and yet the etiology of …

[HTML][HTML] Frequency and distribution of corneal astigmatism and keratometry features in adult life: Methodology and findings of the UK Biobank study

…, AC Day, UK Biobank Eye and Vision Consortium - PLoS …, 2019 - journals.plos.org
Purpose To describe corneal astigmatism in the UK Biobank population and to look for
associations with other biometric variables and socio-demographic factors. Methods This …

[HTML][HTML] Temporal trends in frequency, type and severity of myopia and associations with key environmental risk factors in the UK: Findings from the UK Biobank Study

…, JS Rahi, UK Biobank Eye and Vision Consortium - PLoS …, 2022 - journals.plos.org
This study investigated temporal trends in the epidemiology of primary myopia and
associations with key environmental risk factors in a UK population. Data were collected at …

[HTML][HTML] Associations with photoreceptor thickness measures in the UK Biobank

SYL Chua, B Dhillon, T Aslam, K Balaskas, Q Yang… - Scientific reports, 2019 - nature.com
Abstract Spectral-domain OCT (SD-OCT) provides high resolution images enabling
identification of individual retinal layers. We included 32,923 participants aged 40–69 years …

Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

…, PG Hysi, UK Biobank Eye and Vision Consortium… - Nature …, 2018 - nature.com
Glaucoma is the leading cause of irreversible blindness globally. Despite its gravity, the
disease is frequently undiagnosed in the community. Raised intraocular pressure (IOP) is …

[PDF][PDF] Is a large eye size a risk factor for myopia? A Mendelian randomization study

UK Biobank Eye and Vision Consortium. - bioRxiv, 2017 - biorxiv.org
Myopia (nearsightedness) is an increasingly common cause of irreversible visual
impairment. The ocular structures with greatest impact on refractive error are corneal …

[HTML][HTML] GWAS on retinal vasculometry phenotypes

…, UK Biobank Eye and Vision Consortium - PLoS …, 2023 - journals.plos.org
The eye is the window through which light is transmitted and visual sensory signalling
originates. It is also a window through which elements of the cardiovascular and nervous …