Pharmacologic induction of posterior vitreous detachment in the rabbit

TC Verstraeten, C Chapman, M Hartzer… - Archives of …, 1993 - jamanetwork.com
• Objective.—To assay the proteolytic activity of plasmin on the vitreoretinal junction and to
assess a potential facilitating effect on posterior vitreous detachment. Methods.—We …

Plasmin enzyme-assisted vitrectomy in traumatic pediatric macular holes

AR Margherio, RR Margherio, M Hartzer, MT Trese… - Ophthalmology, 1998 - Elsevier
OBJECTIVE: This study aimed to evaluate the benefit of plasmin enzyme-assisted macular
hole surgery on a consecutive series of pediatric patients with traumatic macular holes …

Identification of missense mutations in the Norrie disease gene associated with advanced retinopathy of prematurity

BS Shastry, SD Pendergast, MK Hartzer… - Archives of …, 1997 - jamanetwork.com
Background: Retinopathy of prematurity (ROP) is a retinal vascular disease occurring in
infants with short gestational age and low birth weight and can lead to retinal detachment …

An overview of potential applications of heparin in vitreoretinal surgery

MS BLUMENKRANZ, MK HARTZER, D IVERSON - Retina, 1992 - journals.lww.com
Heparin is a naturally occurring complex polysaccharide with properties that lend
themselves to the potential treatment of proliferative ocular disorders. The biochemistry of …

Autologous plasmin enzyme in the surgical management of diabetic retinopathy

JG Williams, MT Trese, GA Williams, MK Hartzer - Ophthalmology, 2001 - Elsevier
PURPOSE: This is a pilot study to assess the use of autologous plasmin enzyme (APE) as
an adjunct to vitreous surgery in eyes with advanced diabetic retinopathy. DESIGN …

X-linked recessive familial exudative vitreoretinopathy

DA Plager, IK Orgel, FD Ellis, M Hartzer… - American journal of …, 1992 - Elsevier
Familial exudative vitreoretinopathy is an inherited disorder characterized by retinal traction,
peripheral vitreous opacities, and subretinal and intraretinal exudates. We observed a family …

A new approach to stage 3 macular holes

MT Trese, GA Williams, MK Hartzer - Ophthalmology, 2000 - Elsevier
PURPOSE: The purpose of this article is to demonstrate the feasibility of a surgical approach
that might be possible in an office setting for idiopathic stage 3 macular holes. The posterior …

Inhibition of intraocular fibrin formation following infusion of low-molecular-weight heparin during vitrectomy

DA Iverson, H Katsura, MK Hartzer… - Archives of …, 1991 - jamanetwork.com
• We studied the inhibition of intraocular fibrin formation following infusion of 5 IU/mL of low-
molecular-weight heparin sodium (Fragmin, Kabi-Vitrum AB, Stockholm, Sweden) during …

Assembly of vimentin in vitro and its implications concerning the structure of intermediate filaments

W Ip, MK Hartzer, YYS Pang, RM Robson - Journal of molecular biology, 1985 - Elsevier
After dialysis against 10 m m-Tris-acetate (pH 8.5), vimentin that has been purified in the
presence of urea is present in the form of tetrameric 2 to 3 nm× 48 nm rods known as …

Treatment of ligneous conjunctivitis with topical plasmin and topical plasminogen

DG Heidemann, GA Williams, M Hartzer, A Ohanian… - Cornea, 2003 - journals.lww.com
Treatment of Ligneous Conjunctivitis with Topical Plasmin an... : Cornea Treatment of Ligneous
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