Aetiological and immunological aspects of AMD, a leading cause of blindness in Western
countries, have been reviewed. Developmental studies suggest that anatomical features …

Resident microglial cells can be regarded as the immunological watchdogs of the brain and
the retina. They are active sensors of their neuronal microenvironment and rapidly respond …

Human and macaque retinae have similar retinal vascular anatomy. The general features of
the retinal vascular anatomy of these two primates have much in common with more widely …

Geographic atrophy (GA), an untreatable advanced form of age-related macular
degeneration, results from retinal pigmented epithelium (RPE) cell degeneration. Here we …

Presence of a fovea centralis is directly linked to molecular specification of an avascular
area in central retina, before the fovea (or 'pit') begins to form. Modelling suggests that …

The mammalian retina, like the rest of the central nervous system, is highly stable and can
maintain its structure and function for the full life of the individual, in humans for many …

The central retina in primates is adapted for high acuity vision. The most significant
adaptations to neural retina in this respect are: 1. The very high density of cone …

Neurogenesis in the ventricular layer and the development of cell topography in the
ganglion cell layer have been studied in whole‐mounts of human fetal retinae. At the end of …

We have estimated the number of axons in the optic nerves of human fetuses ranging in
gestational age from approximately 10 to 33 weeks. At 10–12 weeks of gestation there were …

We have investigated the relationships of the cellular constituents of the retinal vasculature—
astrocytes, microglia and pericytes—to the differentiating endothelium in human fetal retina …