User profiles for "author:Itay Chowers"

Itay Chowers

Chairman Department of Ophthalmoloy Hadassah Medical Center
Verified email at hadassah.org.il
Cited by 6297

Adult-onset foveomacular vitelliform dystrophy: a fresh perspective

I Chowers, L Tiosano, I Audo, M Grunin… - Progress in retinal and …, 2015 - Elsevier
Adult-onset foveomacular vitelliform dystrophy (AFVD) was first described by Gass four
decades ago. AFVD is characterized by subretinal vitelliform macular lesions and is usually …

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

LG Fritsche, W Igl, JNC Bailey, F Grassmann… - Nature …, 2016 - nature.com
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …

[PDF][PDF] Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration

A Sene, AA Khan, D Cox, REI Nakamura, A Santeford… - Cell metabolism, 2013 - cell.com
Pathologic angiogenesis mediated by abnormally polarized macrophages plays a central
role in common age-associated diseases such as atherosclerosis, cancer, and macular …

Treatment options in the management of choroidal metastases

R Amer, J Pe'er, I Chowers, I Anteby - Ophthalmologica, 2004 - karger.com
We performed a retrospective study of 40 consecutive patients (50 eyes) treated for
choroidal metastases of solid systemic malignancies in order to evaluate treatment results …

Ophthalmology practice during the COVID-19 pandemic

K Safadi, JM Kruger, I Chowers… - BMJ open …, 2020 - bmjophth.bmj.com
Objective To present an established practice protocol for safe and effective hospital-setting
ophthalmic practice during the coronavirus disease 2019 (COVID-19) pandemic. Methods …

Clinical impact of the worldwide shortage of verteporfin (Visudyne®) on ophthalmic care

MJ Sirks, EHC van Dijk, N Rosenberg… - Acta …, 2022 - Wiley Online Library
Abstract Introduction Since July 2021, a worldwide shortage of verteporfin (Visudyne®)
occurred: an essential medicine required for photodynamic therapy (PDT). PDT with …

[HTML][HTML] Beyond the complement cascade: insights into systemic immunosenescence and inflammaging in age-related macular degeneration and current barriers to …

AH Khan, I Chowers, AJ Lotery - Cells, 2023 - mdpi.com
Landmark genetic studies have revealed the effect of complement biology and its regulation
on the pathogenesis of age-related macular degeneration (AMD). Limited phase 3 clinical …

[PDF][PDF] Homozygosity mapping reveals null mutations in FAM161A as a cause of autosomal-recessive retinitis pigmentosa

D Bandah-Rozenfeld, L Mizrahi-Meissonnier… - The American Journal of …, 2010 - cell.com
Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal degenerations
caused by mutations in at least 45 genes. Using homozygosity mapping, we identified a∼ 4 …

[HTML][HTML] Lack of BRAF mutation in primary uveal melanoma

Y Cohen, N Goldenberg-Cohen, P Parrella… - … & visual science, 2003 - arvojournals.org
purpose. BRAF T1796A activating mutations have been found in a high proportion of
cutaneous melanomas, cutaneous nevi, and papillary thyroid carcinoma and in a small …

Proliferative activity and p53 expression in primary and recurrent pterygia

I Chowers, J Pe'er, E Zamir, N Livni, M Ilsar… - Ophthalmology, 2001 - Elsevier
PURPOSE: To assess p53 expression and proliferative activity in primary and recurrent
pterygia from the same eyes. DESIGN: Retrospective comparative human tissue study …