User profiles for "author:Caroline Brandl"
 | PD Dr. Caroline Brandl, MD, FEBOUniversity Eye Clinic Regensburg Verified email at ukr.de Cited by 3445 |
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …
[HTML][HTML] A deep learning algorithm for prediction of age-related eye disease study severity scale for age-related macular degeneration from color fundus photography
F Grassmann, J Mengelkamp, C Brandl, S Harsch… - Ophthalmology, 2018 - Elsevier
Purpose Age-related macular degeneration (AMD) is a common threat to vision. While
classification of disease stages is critical to understanding disease risk and progression …
classification of disease stages is critical to understanding disease risk and progression …
Comparison of human dental follicle cells (DFCs) and stem cells from human exfoliated deciduous teeth (SHED) after neural differentiation in vitro
C Morsczeck, F Völlner, M Saugspier, C Brandl… - Clinical oral …, 2010 - Springer
Dental stem cells from human exfoliated deciduous teeth (SHED) and dental follicle cells
(DFCs) are neural crest-derived stem cells from human dental tissues. Interestingly, SHED …
(DFCs) are neural crest-derived stem cells from human dental tissues. Interestingly, SHED …
Bestrophin 1 is indispensable for volume regulation in human retinal pigment epithelium cells
In response to cell swelling, volume-regulated anion channels (VRACs) participate in a
process known as regulatory volume decrease (RVD). Only recently, first insight into the …
process known as regulatory volume decrease (RVD). Only recently, first insight into the …
[HTML][HTML] In-depth characterisation of Retinal Pigment Epithelium (RPE) cells derived from human induced pluripotent stem cells (hiPSC)
C Brandl, SJ Zimmermann, VM Milenkovic… - Neuromolecular …, 2014 - Springer
Induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) has widely
been appreciated as a promising tool to model human ocular disease emanating from …
been appreciated as a promising tool to model human ocular disease emanating from …
Association of smoking, alcohol consumption, blood pressure, body mass index, and glycemic risk factors with age-related macular degeneration: a Mendelian …
V Kuan, A Warwick, A Hingorani, A Tufail… - JAMA …, 2021 - jamanetwork.com
Importance Advanced age-related macular degeneration (AMD) is a leading cause of
blindness in Western countries. Causal, modifiable risk factors need to be identified to …
blindness in Western countries. Causal, modifiable risk factors need to be identified to …
[HTML][HTML] A circulating microrna profile is associated with late-stage neovascular age-related macular degeneration
F Grassmann, PGA Schoenberger, C Brandl, T Schick… - PloS one, 2014 - journals.plos.org
Age-related macular degeneration (AMD) is the leading cause of severe vision impairment
in Western populations over 55 years. A growing number of gene variants have been …
in Western populations over 55 years. A growing number of gene variants have been …
[HTML][HTML] Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease
Background Advanced age-related macular degeneration (AMD) is a leading cause of
blindness. While around half of the genetic contribution to advanced AMD has been …
blindness. While around half of the genetic contribution to advanced AMD has been …
[HTML][HTML] Retinal layer thicknesses in early age-related macular degeneration: results from the German AugUR Study
Purpose: To systematically analyze thicknesses of retinal layers in an older population and
their link to early age-related macular degeneration (AMD). Methods: In the AugUR baseline …
their link to early age-related macular degeneration (AMD). Methods: In the AugUR baseline …
[HTML][HTML] Features of age-related macular degeneration in the general adults and their dependency on age, sex, and smoking: results from the German KORA study
C Brandl, V Breinlich, KJ Stark, S Enzinger… - PloS one, 2016 - journals.plos.org
Age-related macular degeneration (AMD) is a vision impairing disease of the central retina
characterized by early and late forms in individuals older than 50 years of age. However …
characterized by early and late forms in individuals older than 50 years of age. However …