Neuro-ophthalmic manifestations of coronavirus disease 19

AK Tisdale, BK Chwalisz - Current Opinion in Ophthalmology, 2020 - journals.lww.com
The literature on COVID-19 continues to evolve. Although COVID-19 primarily impacts the
respiratory system, there are several reports of new onset neuro-ophthalmic conditions in …

Afferent and efferent neuro-ophthalmic complications of coronavirus disease 19

AK Tisdale, M Dinkin, BK Chwalisz - Journal of Neuro …, 2021 - journals.lww.com
Purpose: To provide a summary of the neuro-ophthalmic manifestations of coronavirus
disease 19 (COVID-19) documented in the literature thus far. Methods: The PubMed and …

[HTML][HTML] Treatment and relapse prevention of typical and atypical optic neuritis

G Saitakis, BK Chwalisz - International Journal of Molecular Sciences, 2022 - mdpi.com
Optic neuritis (ON) is an inflammatory condition involving the optic nerve. Several important
typical and atypical ON variants are now recognized. Typical ON has a more favorable …

[HTML][HTML] Consensus disease definitions for neurologic immune-related adverse events of immune checkpoint inhibitors

AC Guidon, LB Burton, BK Chwalisz… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Expanding the US Food and Drug Administration–approved indications for immune
checkpoint inhibitors in patients with cancer has resulted in therapeutic success and …

Association between immunosuppressive treatment and outcomes of cerebral amyloid angiopathy–related inflammation

RW Regenhardt, JM Thon, AS Das, OR Thon… - JAMA …, 2020 - jamanetwork.com
Importance Cerebral amyloid angiopathy–related inflammation (CAA-ri), a distinct subtype of
cerebral amyloid angiopathy, is characterized by an autoimmune reaction to …

Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy

NJ Newman, P Yu-Wai-Man, PS Subramanian… - Brain, 2023 - academic.oup.com
Leber hereditary optic neuropathy (LHON) is an important example of mitochondrial
blindness with the m. 11778G> A mutation in the MT-ND4 gene being the most common …

[HTML][HTML] Indirect comparison of lenadogene nolparvovec gene therapy versus natural history in patients with Leber hereditary optic neuropathy carrying the m. 11778G …

V Carelli, NJ Newman, P Yu-Wai-Man… - Ophthalmology and …, 2023 - Springer
Introduction Lenadogene nolparvovec is a promising novel gene therapy for patients with
Leber hereditary optic neuropathy (LHON) carrying the m. 11778G> A ND4 mutation (MT …

Optic perineuritis

G Saitakis, BK Chwalisz - Current Opinion in Ophthalmology, 2022 - journals.lww.com
Unlike optic nerve, OPN is not typically self-limited without treatment. High-dose oral
corticosteroids are the mainstay of treatment in OPN. The initiation of therapy usually causes …

[HTML][HTML] Safety of lenadogene nolparvovec gene therapy over 5 years in 189 patients with Leber hereditary optic neuropathy

C Vignal-Clermont, P Yu-Wai-Man, NJ Newman… - American Journal of …, 2023 - Elsevier
Purpose To evaluate the safety profile of lenadogene nolparvovec (Lumevoq) in patients
with Leber hereditary optic neuropathy. Design Pooled analysis of safety data from 5 clinical …

Neuro-ophthalmic complications of varicella-zoster virus

TO Tofade, BK Chwalisz - Current Opinion in Ophthalmology, 2023 - journals.lww.com
Neuro-ophthalmic complications of varicella-zoster virus : Current Opinion in Ophthalmology
Neuro-ophthalmic complications of varicella-zoster virus : Current Opinion in Ophthalmology …