Clinical evaluation of corneal biomechanical parameters after posterior chamber phakic intraocular lens implantation

Cornea. 2014 May;33(5):470-4. doi: 10.1097/ICO.0000000000000088.

Abstract

Purpose: The aim of this study was to quantitatively assess the changes in corneal biomechanics after posterior chamber phakic intraocular lens (Visian ICL; STAAR Surgical) implantation for normal and keratoconic subjects.

Methods: We retrospectively examined 29 eyes of 16 consecutive patients (mean age ± SD, 32.4 ± 7.3 years) undergoing implantable collamer lens (ICL) implantation through a 3.0-mm temporal corneal incision. We longitudinally assessed the values of corneal hysteresis (CH) and corneal resistance factor (CRF) using an Ocular Response Analyzer. We also investigated the relationship between these biomechanical parameters and central corneal thickness (CCT) preoperatively, and at 1 week, 1 month, and 3 months postoperatively.

Results: The CH was 9.2 ± 1.4 mm Hg preoperatively, and 9.2 ± 1.4 mm Hg, 9.3 ± 1.7 mm Hg, and 8.8 ± 1.3 mm Hg at 1 week, 1 month, and 3 months postoperatively, respectively. The CRF was 8.4 ± 1.6 mm Hg preoperatively, and 9.0 ± 1.5 mm Hg, 8.8 ± 1.7 mm Hg, and 8.8 ± 1.6 mm Hg, at 1 week, 1 month, and 3 months postoperatively, respectively. Multiple comparisons demonstrated no significant differences between measurements made preoperatively and postoperatively (P > 0.05, Dunnett test). Both CH and CRF were significantly correlated with CCT 3 months postoperatively [Spearman correlation coefficient (r) = 0.48, P = 0.01 for CH; r = 0.84, P < 0.001 for CRF].

Conclusions: We found no significant changes in CH or CRF after ICL implantation, not only in normal eyes but also in keratoconic eyes, suggesting that this surgical technique does not significantly affect corneal biomechanical factors. The CCT may play some role in corneal biomechanics even in eyes undergoing ICL implantation.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Biomechanical Phenomena / physiology*
  • Cornea / physiology*
  • Female
  • Healthy Volunteers
  • Humans
  • Iridectomy
  • Iris / surgery
  • Keratoconus / physiopathology
  • Keratoconus / surgery*
  • Lasers, Solid-State
  • Lens Implantation, Intraocular*
  • Male
  • Middle Aged
  • Phakic Intraocular Lenses*
  • Retrospective Studies
  • Young Adult