Purpose: To report the first case of sarcoid-related uveitis in a patient receiving adalimumab.
Design: Case report.
Methods: A 61-year-old woman with rheumatoid arthritis treated with adalimumab for 4 years presented with a 1-year history of bilateral panuveitis with venous vasculitis and peripheral multifocal choroiditis. A small papular lesion was found on her forehead, which upon biopsy showed noncaseating granulomas. No systemic involvement was observed.
Results: An ophtalmological and clinical improvement was seen after (TNF) antagonist withdrawal plus a course of prednisone.
Conclusions: Ophthalmologists should know that a sarcoid-like granulomatosis can develop during TNFα blockade therapy.