Corneal cross linking for keratoconus

Semin Ophthalmol. 2010 Sep-Nov;25(5-6):249-55. doi: 10.3109/08820538.2010.518503.

Abstract

Riboflavin-induced ultraviolet light (UV) cross linking has received a significant amount of attention in recent years. It is currently approved in Europe as a treatment for keratoconus and is also being used for other corneal disorders. The goal of this paper is to review in detail seminal papers and studies that have been done to support cross linking as a safe and effective treatment for patients with early stages of keratoconus.

Publication types

  • Review

MeSH terms

  • Collagen / metabolism*
  • Corneal Stroma / metabolism*
  • Cross-Linking Reagents*
  • Humans
  • Keratoconus / drug therapy*
  • Keratoconus / metabolism
  • Photochemotherapy*
  • Photosensitizing Agents* / therapeutic use
  • Riboflavin / therapeutic use
  • Ultraviolet Rays*

Substances

  • Cross-Linking Reagents
  • Photosensitizing Agents
  • Collagen
  • Riboflavin