Original articleComplications, Adverse Events, and Additional Intraocular Surgery 1 Year After Cataract Surgery in the Infant Aphakia Treatment Study
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Patients and Methods
The study design, surgical techniques, follow-up schedule, and patient characteristics at baseline have been reported in detail previously and are only summarized here.7 This study was approved by the institutional review boards of all participating institutions and was in compliance with the Health Insurance Portability and Accountability Act. The off-label research use of the AcrySof SN60AT and MA60AC IOLs (Alcon Laboratories, Fort Worth, TX) was covered by United States Food and Drug
Intraoperative Complications
There were more patients with ICs reported in the IOL group, 16 (21%), than the CL group, 6 (11%; P = 0.031). There were a total of 22 ICs in 16 IOL patients. Of these, iris prolapse was the most common (n = 12), followed by iris damage (n = 3), and hyphema (n = 2). There was one occurrence each of retained cortex, corneal clouding, iris sphincterotomy, lens fragment in the vitreous, and inadvertent rupture of the posterior capsule.
More specifically in the IOL group, the following complications
Discussion
The decision regarding whether to implant an IOL in an infant eye at the time of surgery for congenital cataract, as with any surgery, requires balancing the expected benefit of the surgery against the risks associated with the procedure. One of the potential benefits of placing an IOL at the time of infant cataract surgery and the primary outcome measure of the IATS is the visual acuity. At 1 year, the acuity in the 2 groups was not different.8 This measure will be reassessed in all study
References (13)
- et al.
Primary intraocular lens implantation in infants: complications and visual results
J Cataract Refract Surg
(2006) - et al.
Unilateral intraocular lens implantation during the first six months of life
J AAPOS
(1999) - et al.
A comparison of grating visual acuity, strabismus, and reoperation outcomes among children with aphakia and pseudophakia after unilateral cataract surgery during the first six months of life
J AAPOS
(2001) - et al.
Complications in the first year following cataract surgery with and without IOL in infants and older children
J AAPOS
(2002) - et al.
Opacification of the visual axis after cataract surgery and single acrylic intraocular lens implantation in the first year of life
J AAPOS
(2004) - et al.
Does primary intraocular lens implantation prevent “aphakic” glaucoma in children?
JAAPOS
(2000)
Cited by (0)
Members of the Infant Aphakia Treatment Study Group are listed in Appendix 1, available at http://aaojournal.org.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by the National Institutes of Health, Bethesda, Maryland (grant nos.: U10 EY13272 and U10 EY013287; and Departmental Core Grant no.: EY06360); and in part by Research to Prevent Blindness, Inc., New York, New York.
Manuscript no. 2011-483.