Original articleUpdate on Bacterial Conjunctivitis in South Florida
Section snippets
Materials and Methods
A retrospective chart review of microbiology records was conducted for all patients who underwent a diagnostic conjunctival culture for suspect bacterial conjunctivitis by clinicians at Bascom Palmer Eye Institute from January 1, 1994 through December 31, 2003. Samples were collected according to standard Bascom Palmer Eye Institute protocol (Miller, unpublished data). The study was approved by the human subjects medical sciences subcommittee of the University of Miami School of Medicine
Results
There were a total of 1254 culture-positive isolates identified of 2408 consecutive conjunctival cultures evaluated for acute bacterial conjunctivitis between 1994 and 2003 at Bascom Palmer Eye Institute. The culture-positive rate for bacterial conjunctivitis was 52.1%.
Gram-positive pathogens accounted for 52.5% of isolates, versus 47.8% of gram-negative isolates. The percentage of gram-positive isolates ranged from 56.2% to 48.1% from the first 5 years to the second 5 years (P = 0.002). The
Discussion
The ratio of gram-positive to gram-negative isolates was consistent throughout the length of the study. Although the overall male-to-female ratio was 1:1, 49% of males had gram-positive organisms, compared with 56% of females (P = 0.031). This finding is not supported by previous literature and therefore may be spurious, making it unlikely to be highly significant. The most frequent isolates were S. aureus, H. influenzae, S. pneumoniae, P. aeruginosa, S. viridans, and P. mirabilis.
References (9)
- et al.
Shifting trends in in vitro antibiotic susceptibilities for common ocular isolates during a period of 15 Years
Am J Ophthalmol
(2004) - et al.
Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones
Ophthalmology
(2000) - et al.
Bacterial conjunctivitis
- et al.
Bacterial conjunctivitis
Clin Evid
(2002)
Cited by (99)
Ocular streptococcal infections: A clinical and microbiological review
2023, Survey of OphthalmologyMicrobiological profile of canaliculitis and their antibiotic susceptibility patterns: A 11-year review at a referral eye care centre
2022, Indian Journal of Medical MicrobiologyMicrobes of the human eye: Microbiome, antimicrobial resistance and biofilm formation
2021, Experimental Eye ResearchConjunctivitis Preferred Practice Pattern®
2019, OphthalmologyGender and Ethnicity of Enrolled Participants in U.S. Food and Drug Administration (FDA) Clinical Trials for Approved Ophthalmological New Molecular Entities
2018, Journal of the National Medical AssociationCitation Excerpt :The indications for the 9 approved NME trials over the last 10 years were: dry eye disease, open angle glaucoma/ocular hypertension, vitreomacular adhesion, neovascular age related macular degeneration, allergic conjunctivitis, pain and inflammation after ocular surgery, and bacterial conjunctivitis. Among those 7 indications, two are not known to have any interactions with race or gender: post-operative ocular pain/inflammation14 and bacterial conjunctivitis.15,16 It is known that gender and race play a role in dry eye disease.
Manuscript no. 2006-856.
Supported in part by a grant from Research to Prevent Blindness, New York, New York.