Journal of American Association for Pediatric Ophthalmology and Strabismus
Major articleIncidence and Risk Factors for Glaucoma After Pediatric Cataract Surgery With and Without Intraocular Lens Implantation
Section snippets
Subjects and methods
A retrospective database review was performed for 470 consecutive eyes in patients that underwent pediatric cataract surgery with IOL implantation and 91 eyes in patients without an IOL implant between March 1991 and October 2004. Institutional review board approval was obtained to use our database for research purposes. The eyes of children with traumatic cataract, aniridia, Lowe syndrome, steroid-induced cataract, lens subluxation, uveitis, retinoblastoma, radiation-induced cataract,
Results
Two hundred sixty-six eyes with primary IOL implantation after cataract surgery were included in the primary analysis. Follow-up of these 266 eyes ranged from 1 to 145.6 months. During initial analysis, we noted that the 10 pseudophakic eyes that developed glaucoma underwent cataract surgery at 4.5 months of age or younger. The average follow-up in those children older than 4.5 months of age who underwent surgery was 40.8 months versus 43.2 months for those children who were 4.5 months or
Discussion
The incidence of glaucoma in children with aphakic eyes has been reported to be 5% to 41%.1, 3, 5, 6, 8, 15, 17, 18 However, the effect of IOL implantation on the incidence of glaucoma after cataract surgery is unclear. In a multicenter retrospective review, Asrani and coworkers23 reported a lower incidence (0.3%, or 1 in 377 cases) of open-angle glaucoma in eyes receiving a primary IOL implant compared with those that remained aphakic (11.3%, or 14 in 124 cases) after cataract surgery. In the
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Cited by (0)
Supported in part by NIH/NEI grant EY-14793; an unrestricted grant to MUSC from Research to Prevent Blindness, Inc., NY, NY; and the Grady Lyman Fund of the MUSC Health Sciences Foundation, Charleston, SC. The authors acknowledge the critical manuscript review of Luanna Bartholomew, Ph.D.