International Journal of Oral and Maxillofacial Surgery
Clinical Paper
TraumaA prospective comparison of octyl-2-cyanoacrylate and suture in standardized facial wounds
Trauma
Section snippets
Material and methods
To compare very similar facial wounds of nearly equal length, localization and shape, the infraorbital cut (lower eyelid) was used. Forty-five Caucasian patients with an orbital floor fracture were included in this investigation. Patients were eligible for inclusion in the study if they were of generally good health without significant systemic abnormalities, had the medical indication for a surgical orbital floor reconstruction and provided informed consent. The study report meets the criteria
Results
A total of 45 patients met the previously defined inclusion criteria and were examined about 3 months after surgery. In 19 patients, wound closure was performed with a skin adhesive (Dermabond®) and in 26 patients with a monofilament suture (Ethilon®). The two treatment groups were similar regarding age, duration of surgery and follow-up time. The mean age of the patients in the adhesive group was 47 years against 42 years in the suture group. The total surgical procedure took 63 min (skin
Discussion
Tissue adhesives are an area of tremendous interest and research. The use of skin adhesives has become very popular, particularly for paediatric patients. Cyanoacrylates used as skin adhesives are liquid monomers that polymerize into a solid material forming a thin film that causes the opposite edges of a wound to adhere. While the short-chain cyanoacrylates (methyl and ethyl forms) have been associated with tissue toxicity as a result of rapid degradation, the higher chain derivatives (such as
References (24)
- et al.
Which tissue adhesive for wounds?
Injury
(2003) - et al.
Use of tissue adhesives in the repair of lacerations in children
J Pediatr Surg
(1988) - et al.
The efficacy of cyanoacrylate-derived surgical adhesive for use in the repair of lacerations during competitive athletics
Am J Emerg Med
(2000) - et al.
Appearance scales to measure cosmetic outcomes of healed lacerations
Am J Emerg Med
(1995) Methods and materials for wound closure
Otolaryngol Clin North Am
(1995)- et al.
Level of training, wound care practices, and infection rates
Am J Emerg Med
(1995) - et al.
A prospective comparison of octyl cyanoacrylate tissue adhesive (dermabond) and suture for the closure of excisional wounds in children and adolescents
Arch Dermatol
(2001) - et al.
Analysis of dental plaster casts by computer-controlled phase-shifting profilometry [in German]
Dtsch Zahnärztl Z
(1997) - et al.
Chemistry and performance of cyanoacrylate adhesive
Special Tech Papers
(1959) - et al.
The ideal tissue adhesive in facial plastic and reconstructive surgery
J Otolaryngol
(1990)
The current status of tissue glues: part II. For adhesion of soft tissues
Plast Reconstr Surg
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Conventional skin suture, skin staple versus contemporary tissue adhesive for maxillofacial elective wound care—A single blind prospective randomized comparative study
2021, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyCitation Excerpt :The mean scores of all three groups were compared and the difference was statistically analyzed. The cosmetic outcome was assessed by a dermatologist (investigator I) and an oral and maxillofacial surgeon (investigator II) using modified Hollander Wound Evaluation Scale (HWES) [9,10] (Table 1) and by the patients themselves using the Visual Analog Scale (VAS) [11,12] three months after the wound closure. For the wound evaluation scale, both investigators were blinded to the study (unaware of the closure method used), asked to inspect each wound and assign the number 0 or 1 each for the presence or absence
Randomized Controlled Trial of Octyl Cyanoacrylate Skin Adhesive versus Subcuticular Suture for Skin Closure after Implantable Venous Port Placement
2017, Journal of Vascular and Interventional RadiologyCitation Excerpt :VAS scores at 3 months have been shown to have strong agreement with VAS scores at 12 months (22), and these results may be expected to be maintained over the longer term. However, a study analyzing cosmesis of infraorbital incisions that randomly assigned patients to skin adhesive versus 6-0 nylon suture reported similar VAS scores between groups, although with greater scar depression with skin adhesive (0.47 mm vs 0.21 mm; P < .05) (14). Although the costs of supplies for the 2 skin closure methods were calculated, the overall cost implications were not rigorously assessed in this study.
Comparing cyanoacrylate tissue adhesive and conventional subcuticular skin sutures for maxillofacial incisions - A prospective randomized trial considering closure time, wound morbidity, and cosmetic outcome
2013, Journal of Oral and Maxillofacial SurgeryCitation Excerpt :The results of the surgeon's VAS was obtained by an analysis of 3-month postoperative photographs and showed equivalent cosmetic results of incision closure with 2-OCA (80.11 ± 10.582 mm) compared with the control group treated with suturing (83.20 ± 8.782 mm; P = .332), with no significant differences (Fig 1-6). Ong et al21 performed a study on pediatric surgical incisions, Handschel et al22 a study on facial wounds, Nipshagen et al23 a study on wound closure after reduction mammaplasty, Sniezek et al24 a study on repairing facial wounds after Mohs micrographic surgery, and Matin14 a study on laparoscopic port-site incisions, and these studies found no significant difference between groups on VAS score, which is similar to the present study. The esthetic prominence of facial scars combined with their emotional and psychological effects demand a continual effort to avoid injury to the wound margins during surgery and closure of the wound.
Use of Tissue Glue for Surgical Incision Closure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
2010, Journal of the American College of SurgeonsCitation Excerpt :Seventy-seven studies were searched in full and 51 additional studies were excluded from the analysis (see Fig. 1). This left 26 studies for evaluation in full,7,12-36 including a total of 2,105 patients and 2,637 wounds. Of the 26 included studies (Table 1), 21 studied adult subjects,7,12,13,15-19,26-26,28-33,36 3 studied pediatric subjects,14,27,35 and 2 studies included adult and pediatric patients.20,34
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