Original articleSuccess Rates of Trabeculotomy for Steroid-Induced Glaucoma: A Comparative, Multicenter, Retrospective Cohort Study
Section snippets
Patient Selection and Surgical Procedures
We retrospectively reviewed the medical records of patients with steroid-induced glaucoma who underwent trabeculotomy or trabeculectomy with MMC and those with POAG who underwent trabeculotomy between January 1, 1997, and December 31, 2006, at the following 17 clinical centers in Japan: Kumamoto University Hospital (Kumamoto), Niigata University Medical and Dental Hospital (Niigata), University of Tokyo Hospital (Tokyo), Kanazawa University Hospital (Kanazawa), Gifu University Hospital (Gifu),
Patient Characteristics
In total, 163 patients (163 eyes) with steroid-induced glaucoma and 108 patients (108 eyes) with POAG satisfied the study criteria. All eligible patients were Japanese. Of the 163 eyes with steroid-induced glaucoma, 121 were included in the steroid-induced glaucoma with trabeculotomy group and 42 were included in the steroid-induced glaucoma with trabeculectomy group. Table 1 lists the characteristics of the enrolled patients.
The steroid-induced glaucoma with trabeculotomy group was
Discussion
This study compared the success rates of trabeculotomy for steroid-induced glaucomatous eyes with those for trabeculectomy for steroid-induced glaucoma eyes, and for trabeculotomy for POAG eyes. Trabeculotomy showed a significantly higher cumulative probability of success in steroid-induced glaucoma patients than POAG patients for both criterion A (P = .0008) and criterion B (P < .0001). The probability of success in steroid-induced glaucoma eyes treated with trabeculotomy was comparable to
Keiichiro Iwao, MD, PhD, received his doctorate from Saga University's Graduate School of Medicine, Saga, Japan, in 2009, which was based on mouse models of developmental glaucoma. He is currently assistant professor in the Department of Ophthalmology, Saga University Faculty of Medicine. He has been recognized by the Association for Research in Vision and Ophthalmology and was a recipient of the 2009 Kowa Travel Grant Award. His interests include glaucoma surgery and regeneration of the optic
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Keiichiro Iwao, MD, PhD, received his doctorate from Saga University's Graduate School of Medicine, Saga, Japan, in 2009, which was based on mouse models of developmental glaucoma. He is currently assistant professor in the Department of Ophthalmology, Saga University Faculty of Medicine. He has been recognized by the Association for Research in Vision and Ophthalmology and was a recipient of the 2009 Kowa Travel Grant Award. His interests include glaucoma surgery and regeneration of the optic nerve.