Original articleThe Epidemiology of Retinal Reticular Drusen
Section snippets
Population
Methods used to identify the population and descriptions of the population have appeared in previous reports.9, 10, 11, 12, 13 A private census of the population of Beaver Dam, Wisconsin (99% White), was performed from fall 1987 through spring 1988.9 Of the 5,924 enumerated persons aged 43 to 84 years, 4,926 (83.2%) participated in the baseline examination from 1988 through 1990.10 Of these, 3,684 (81.1%) participated in the five-year follow-up examination from 1993 through 1995.11 Comparisons
Prevalence
Reticular drusen were present in 0.7% of the cohort at baseline, and the frequency was similar in the right (0.7%) and left (0.5%) eyes. Of the 32 people at baseline with reticular drusen, 20 (63%) had it in both eyes. When present, they were found outside the macula defined by the grid 81% of the time (Figure 2, Left). When present in the macular area, they were found most commonly in the outer superior subfield 74% of the time, in the outer temporal subfield 70% of the time, and never in the
Discussion
Using standardized detailed procedures for obtaining stereoscopic color fundus photographs of the macula and an objective system for grading those photographs for AMD, we found a prevalence of reticular drusen of 0.7% and a 15-year cumulative incidence, accounting for the competing risk of death, of 3.0% in the Beaver Dam population aged 43 to 86 years of age at baseline. In addition, we report a high 15-year cumulative incidence of late AMD (43% and 46% in right and left eyes, respectively)
Dr Ronald Klein is a Professor of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health and is interested in ocular epidemiology of age-related eye disease and hypertensive and diabetic retinopathy.
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2021, Ophthalmology RetinaCitation Excerpt :Reticular pseudodrusen in the CAREDS2 population were seen most frequently occupying 2 or more quadrants or with a superior distribution. Other studies have shown that RPD location most commonly involves the superior arcade.6,27,31 When assessing the RPD location by age tertile, a trend also was found associating older age and global RPD, which was defined as RPD occupying 2 quadrants or more.
Dr Ronald Klein is a Professor of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health and is interested in ocular epidemiology of age-related eye disease and hypertensive and diabetic retinopathy.