Age-related macular degeneration: economic burden and value-based medicine analysis+
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2021, Clinical TherapeuticsCitation Excerpt :The SIGN level of evidence was B (n = 3) or C (n = 3; ie, well-conducted case-control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal) (Supplemental Table III). For risk of bias, only 1 study complied with ≥30% of criteria41; none of the studies assessed the economic impact of treatment, so some questions were not applicable (Supplemental Table V). The limitations of the reviewed studies were not expected to significantly affect major outcomes.
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This article has been peer-reviewed.
Copyright © 2005 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.