Skip to main content
Log in

The relationship between intraocular pressure and visual field progression in glaucoma

  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

The purpose of this study was to determine the intraocular pressure characteristics in glaucoma suspects and patients whose visual fields were classified as stable or progressing over a long-term follow-up. We present data from 64 patients who received either medical or laser treatment and who were followed up for a median of 7.4 years. The visual fields of 27 patients were classified as stable and 37 as progressing using pre-determined criteria on either the Tübinger or Goldmann perimeter. Patients with initially normal and initially abnormal fields were analysed separately to avoid bias. There were no significant group differences in the mean, highest or interquartile range of intraocular pressure in the follow-up. The largely overlapping distributions over a wide spectrum of the pressure variables in patients with stable and progressing fields show that intraocular pressure alone cannot separate these two groups of patients. Our study does not suggest that pressure reduction in glaucoma has no beneficial effect, but that there may be other factors which determine the fate of the visual field in glaucoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Abedin S, Simmons RJ, Grant WM (1982) Progressive low-tension glaucoma. Treatment to stop glaucomatous cupping and field loss when these progress despite normal intraocular pressure. Ophthalmology 89:1–6

    Google Scholar 

  2. Armaly MF (1969) Ocular pressure and visual fields. A ten year follow-up study. Arch Ophthalmol 81:25–40

    Google Scholar 

  3. Chandler PA (1960) Long-term results in glaucoma therapy. Am J Ophthalmol 49:221–246

    Google Scholar 

  4. Chauhan BC, Drance SM, Douglas GR (1990) The use of visual field indices in detecting changes in the visual field in glaucoma. Invest Ophthalmol Vis Sci 31:512–520

    Google Scholar 

  5. Crick RP, Vogel R, Newson RB, Hunt B, Shipley M, Blackmore H, Bulpitt C (1985) Relationhip between intraocular pressure and visual field progress in chronic simple glaucoma and ocular hypertension. Glaucoma 7:208–219

    Google Scholar 

  6. David R, Livingston D, Luntz MH (1978) Ocular hypertension. A comparative follow-up of black and white patients. Br J Ophthalmol 62:676–678

    Google Scholar 

  7. Flammer J, Drance SM, Augustiny L, Funkhouser A (1985) Quantification of glaucomatous visual field defects with automated perimetry. Invest Ophthalmol Vis Sci 26:176–181

    Google Scholar 

  8. Heijl A, Bengtsson B (1984) The short-term effect of laser trabeculoplasty on the glaucomatous visual field. A prospective study using computerized perimetry. Acta Ophthalmol 62:705–714

    Google Scholar 

  9. Heijl A, Lindgren G, Olsson J (1987) A package for the statistical analysis of visual fields. Doc Ophthalmol Proc Ser 49:153–168

    Google Scholar 

  10. Holmin C, Krakau CET (1980) Visual field decay in normal subjects and in cases of chronic glaucoma. Graefe's Arch Clin Exp Ophthalmol 213:291–298

    Google Scholar 

  11. Holmin C, Storr-Paulsen A (1984) The visual field after trabeculectomy. A follow-up study using computerized perimetry. Acta Ophthalmol 62:230–234

    Google Scholar 

  12. Jerndal T, Lundström M (1977) 330 trabeculectomies — a follow-up study through 1/2–3 years. Acta Ophthalmol 55:52–62

    Google Scholar 

  13. Kitazawa Y, Horie T, Aoki S, Suzuki M, Nishioka K (1977) Untreated ocular hypertension. A long-term prospective study. Arch Ophthalmol 95:1180–1184

    Google Scholar 

  14. Kolker AE (1977) Visual prognosis in advanced glaucoma. A comparison of medical and surgical therapy for retention of vision in 101 eyes with advanced glaucoma. Trans Am Ophthalmol Soc 75:539–555

    Google Scholar 

  15. Kronfeld PC, McGarry HI (1948) Five year follow-up of glaucomas. JAMA 136:957–965

    Google Scholar 

  16. Mao LK, Stewart WC, Shields MB (1991) Correlation between intraocular pressure control and progressive glaucomatous damage in primary open-angle glaucoma. Am J Ophthalmol 111:51–55

    Google Scholar 

  17. Pohjanpelto P (1983) Late results of laser trabeculoplasty for increased intraocular pressure. Acta Ophthalmol 61:998–1008

    Google Scholar 

  18. Pohjanpelto P (1985) Long-term prognosis of visual field in glaucoma simplex and glaucoma capsulare. Acta Ophthalmol 63:418–423

    Google Scholar 

  19. Quigley HA, Maumenee AE (1979) Long-term follow-up of treated open-angle glaucoma. Am J Ophthalmol 87:519–525

    Google Scholar 

  20. Schultz JS, Werner EB, Krupin T, Bishop KI, Koelle J (1987) Intraocular pressure and visual field defects after argon laser trabeculoplasty in chronic open-angle glaucoma. Ophthalmology 94:553–557

    Google Scholar 

  21. Schulzer M, Mikelberg FS, Drance SM (1987) Some observations on the relation between intraocular pressure reduction and progression of glaucomatous visual loss. Br J Ophthalmol 71:486–488

    Google Scholar 

  22. Schulzer M, Mikelberg FS, Drance SM (1987) A study of the value of the central and peripheral isopters in assessing visual field progression in the presence of paracentral scotoma measurements. Br J Ophthalmol 71:422–427

    Google Scholar 

  23. Smith RJH (1972) Medical versus surgical therapy in glaucoma simplex. Br J Ophthalmol 56:277–283

    Google Scholar 

  24. Spaeth GL (1985) The effect of change in intraocular pressure on the natural history of glaucoma. Lowering intraocular pressure in glaucoma can result in improvement of visual fields. Trans Ophthalmol Soc UK 104:256–263

    Google Scholar 

  25. Vogel R, Crick RP, Newson RB, Shipley M, Blackmore H, Bulpitt CJ (1990) Association between intraocular pressure and loss of visual field in chronic simple glaucoma. Br J Ophthalmol 74:3–6

    Google Scholar 

  26. Werner EB, Drance SM (1977) Trabeculectomy and the progression of glaucomatous visual field loss. Arch Ophthalmol 95:1374

    Google Scholar 

  27. Zar JH (1984) Biostatistical analysis. Prentice-Hall, Englewood Cliffs, NJ, pp 122–149

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported in part by grants MT-11357 (Dr. Chauhan) and MT-1576 (Dr. Drance) from the Medical Research Council of Canada. The authors have no proprietary interest in the development or marketing of any instrument used in this study

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chauhan, B.C., Drance, S.M. The relationship between intraocular pressure and visual field progression in glaucoma. Graefe's Arch Clin Exp Ophthalmol 230, 521–526 (1992). https://doi.org/10.1007/BF00181772

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00181772

Keywords

Navigation