Differences in characteristics of those with and without RPD in the Intermediate AMD group
| Intermediate AMD (n=109) | ||||
| RPD | No RPD | OR (95% CI) | P value* | |
| (n=39) | (n=70) | |||
| Female gender | 25 (64%) | 49 (70%) | 0.8 (0.3 to 1.8) | 0.53 |
| Family history of AMD | ||||
| None | 14 (36%) | 40 (57%) | 1 | |
| Yes | 18 (46%) | 18 (26%) | 2.9 (1.2 to 7.1) | |
| Uncertain | 7 (18%) | 12 (17%) | 1.7 (0.5 to 5.0) | 0.07 |
| Age, mean (SD) | 78 (7.1) | 76 (6.7) | 1.0 (0.9 to 1.1) | 0.09 |
| Body mass index, n | 37 | 67 | ||
| Mean (SD) | 26.2 (4.6) | 26.4 (5.1) | 1.0 (0.9 to 1.1) | 0.78 |
| Smoking | ||||
| Never | 16 (41%) | 37 (53%) | 1 | |
| Current | 1 (3%) | 1 (1%) | 2.3 (0.1 to 61) | |
| Former | 22 (56%) | 32 (46%) | 1.6 (0.7 to 3.6) | 0.40† |
| History of | ||||
| Type 2 diabetes | 5 (13%) | 10 (14%) | 0.9 (0.3 to 2.7) | 0.83 |
| Treated hypertension | 29 (74%) | 36 (51%) | 2.7 (1.2 to 6.7) | 0.02 |
| Kidney disease | 8 (21%) | 7 (10%) | 2.3 (0.8 to 7.2) | 0.13 |
| Stroke | 0 (0%) | 6 (9%) | – | 0.09† |
| Peripheral vascular disease | 5 (13%) | 9 (13%) | 1.0 (0.3 to 3.1) | 0.99 |
| Atrial fibrillation | 2 (5%) | 5 (7%) | 0.7 (0.1 to 3.4) | 0.99† |
| Cardiac disease | 17 (44%) | 27 (39%) | 1.2 (0.6 to 2.7) | 0.61 |
*P values obtained from χ2 for categorical variables and t-test for continuous variables unless noted otherwise.
†P values obtained from Fisher’s exact test.
AMD, age-related macular degeneration; RPD, reticular pseudodrusen.