Univariate association testing of abnormal screening results with significant ocular disease using logistic regression
| Clinically significant cataract | POAG (definite) | POAG (definite and suspect) | Significant diabetic retinopathy/maculopathy | Age related macular degeneration | Any sight-threatening eye disease | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Visual acuity<6/12 | 6.69 (3.57 to 12.46) | 4.54 (1.97 to 10.47) | 2.06 (1.04 to 4.06) | NS | 4.88 (2.54 to 9.40) | 4.99 (2.90 to 8.60) |
| Family history of glaucoma | NS | 4.93 (2.19 to 11.09) | 2.92 (1.59 to 5.36) | NS | NS | NS |
| IOP>21 mm Hg | NS | NS | NS | NS | NS | NS |
| FDT≥1 point missed at 1% level | 3.07 (1.72 to 5.47) | 28.69 (8.45 to 97.48) | 6.68 (3.74 to 11.92) | 5.29 (1.25 to 22.48) | 2.95 (1.60 to 5.41) | 5.48 (3.55 to 8.46) |
| FDT≥1 point missed at 5% level | 3.45 (1.91 to 6.23) | 22.21 (5.19 to 95.15) | 5.20 (2.83 to 9.55) | 5.02 (1.00 to 25.11) | 2.75 (1.50 to 5.06) | 4.60 (3.10 to 6.83) |
| SD-OCT (GCC thickness) | NS | 28.64 (10.41 to 78.77) | 7.40 (4.10 to 13.33) | NS | 3.67 (1.93 to 6.96) | 3.77 (2.31 to 6.15) |
| SD-OCT (full retinal thickness) | NS | 5.14 (2.23 to 11.81) | 3.32 (1.90 to 5.81) | 18.06 (2.20 to 148.13) | 2.75 (1.51 to 5.03) | 2.57 (1.72 to 3.84) |
| SD-OCT (peripapillary RNFL thickness) | NS | 39.03 (15.52 to 98.12) | 19.27 (9.57 to 38.82) | NS | 4.41 (2.09 to 9.29) | 7.20 (3.54 to 14.66) |
FDT, frequency-doubling technology; GCC, ganglion cell complex; IOP, intraocular pressure; NS, not significant; POAG, primary open-angle glaucoma; RNFL, retinal nerve fibre layer; SD-OCT, spectral domain optical coherence tomography.