Characteristic | OVD1 (Viscopack 14) | OVD2 (DuoVisc) | ||
Dispersive (BiVisc) | Cohesive (Ocu+ 1.4%) | Dispersive (Viscoat) | Cohesive (ProVisc) | |
Volume (mL) | 0.55 | 1.0 | 0.50 | 0.55 |
pH | 6.5–7.5 | 6.5–7.5 | 7.0–7.4 | 6.8–7.5 |
Osmolality (mOsm/Kg) | 240–400 | 240–400 | 285–365 | 260–360 |
Zero-shear viscosity (mPa*s) | 30 000–80 000 | 30 000–50 000 | 40 000 | 50 000 |
Sodium hyaluronate molecular weight (Dalton) | 3.5–3.8×106 | 3.5–3.8×106 | 5×105 | 2.5×106 |
Composition (per mL) (mg) | ||||
Sodium hyaluronate | 20 | 14 | 30 | 10 |
Sodium chloride | 3.0 | 8.5 | 4.3 | 7.5 |
Disodium hydrogen phoshate | 1.9 | 0.28 | 2.0 | 2.0 |
Sodium dihydrogen phoshate | 0.40 | 0.04 | 0.45 | 0.45 |
Sodium chondroitin sulfate | 30 | – | 40 | – |
Water for injection | q.s. | q.s. | q.s. | q.s. |
Source (sodium hyaluronate) | Bacterial fermentation | Bacterial fermentation | Bacterial fermentation | Bacterial fermentation |
OVD, ophthalmic viscosurgical device; q.s., sufficient quantity.