Table 2

Chemokine receptor expression level frequencies, %, median (IQR)

Response to anti-VEGF loading dose	Good		Partial		Non-response		P value*
CD14⁺CCR1 ⁺	36.9	(19–58.8)	21.7	(12.3–31.5)	63.4	(58.2–57.2)	0.016†
CD14⁺CCR2⁺	93.1	(82.1–97.1)	87.7	(79.4–94)	93.6	(89.2–98.4)	0.169
CD14⁺CCR3⁺	0.4	(0.2–0.6)	0.2	(0.2–0.4)	0.2	(0.2–0.3)	0.103
CD14⁺CCR5⁺	1	(0.3–2.1)	0.7	(0.4–1.4)	1.7	(0.4–2)	0.479
CD14⁺CXCR3⁺	0.9	(0.6–1.7)	0.8	(0.4–1.4)	0.7	(0.4–2.3)	0.414
CD14⁺CX₃CR1⁺	35.9	(26.1–67.3)	40.1	(21.3–64.1)	24.3	(17.3–55)	0.500
CD4⁺CCR1⁺	0.2	(0.2–0.4)	0.1	(0–0.2)	0.1	(0–9.5)	0.591
CD4⁺CCR2⁺	5.1	(4.1–9)	5.1	(3.7–6.6)	7.2	(6.1–8.7)	0.479
CD4⁺CCR3⁺	0.3	(0.2–0.4)	0.2	(0.1–0.3)	0.2	(0.1–0.2)	0.264
CD4⁺CCR5⁺	2.7	(1.2–5.3)	1.8	(1.1–2.5)	4.2	(1.9–7.9)	0.130
CD4⁺CXCR3⁺	2.5	(1.6–5)	3.2	(1–5.1)	2	(1.5–3)	0.645
CD8⁺CCR1⁺	0.2	(0.2–0.4)	0.3	(0.1–0.6)	0.5	(0.1–2.8)	0.811
CD8⁺CCR2⁺	7.8	(4.9–12)	7.5	(5.7–9.2)	7.8	(4.7–8.7)	0.687
CD8⁺CCR3⁺	0.5	(0.4–0.8)	0.4	(0.4–0.7)	0.3	(0.1–0.4)	0.037†
CD8⁺CCR5⁺	12.6	(4.5–23.1)	9.4	(4.7–14.7)	17	(9.6–23.9)	0.195
CD8⁺CXCR3⁺	4	(1.9–6.3)	4.2	(1.3–8.6)	3.3	(1.4–9.1)	0.978