Table 1

Transcripts regulated in the conjunctival epithelium of patients with SJS

Fold changeANOVA P value*Gene accessionGene symbolGene description
Transcripts down-regulated by less than one -fiftieth in the conjunctival epithelium of patients with SJS
−86.970.005NM_001145006MUC7Mucin 7, secreted
−67.010.019NM_002644PIGRPolymeric immunoglobulin receptor
−59.170.021NM_001039372HEPACAM2HEPACAM family member 2
−53.460.019NM_000669ADH1CAlcohol dehydrogenase 1C (class I), gamma polypeptide
−53.250.000NM_012390SMR3ASubmaxillary gland androgen regulated protein 3A
Transcripts upregulated more than 50-fold in the conjunctival epithelium of patients with SJS
193.830.0023NM_002974SERPINB4Serpin peptidase inhibitor, clade B, member 4
173.260.0001NM_006121KRT1Keratin 1
150.70.0007NM_207392KRTDAPKeratinocyte differentiation-associated protein
123.930.0007NM_002963S100A7S100 calcium-binding protein A7
121.690.0019NM_001166034SBSNSuprabasin
96.090.0046NM_002774KLK6Kallikrein-related peptidase 6
91.020.0025NM_080474SERPINB12Serpin peptidase inhibitor, clade B, member 12
89.350.0009NM_001011709PNLIPRP3Pancreatic lipase-related protein 3
85.80.0008NM_012114CASP14Caspase 14, apoptosis-related cysteine peptidase
68.670.0077AK302302ODZ2Odz, odd Oz/ten-m homologue 2
53.440.0146NM_000067CA2Carbonic anhydrase II
53.040.0188NM_019060CRCT1Cysteine-rich C-terminal 1
52.760.0004NM_025087CWH43Cell wall biogenesis 43 C-terminal homologue
51.270.0043NM_002016FLGFilaggrin
  • *Difference from the control.