Demographic and baseline characteristics
| Characteristic | Patients (n=586) |
| Age, years | 79.7 (7.8) |
| Female, n (%) | 358 (61.1) |
| Study eye, n (%) | |
| Right | 310 (52.9) |
| Left | 276 (47.1) |
| Both | 76 (13.0) |
| Duration of wet AMD, months (n=572)* | 1.1 (6.8) |
| BCVA (letters) score (n=502; FAS) | 56.7 (18.2) |
| BCVA (letters) score (n=353; FAS targeted) | 57.7 (17.8) |
| BCVA (letters) score (n=284; FAS targeted with loading dose) | 57.2 (17.8) |
| BCVA (letters) categories, n (%) (n=502) | |
| <50 | 138 (27.5) |
| 50–55 | 63 (12.5) |
| 55–70 | 148 (29.5) |
| ≥70 | 153 (30.5) |
| Central retinal thickness, µm (n=446; FAS)* | 395.6 (140.5) |
| Central retinal thickness, µm (n=346; FAS with loading dose)* | 402.6 (143.1) |
| Subretinal fluid, n (%) (n=474)* | 385 (81.2) |
| Intraretinal fluid, n (%) (n=474)* | 296 (62.4) |
| Pigment epithelium detachment, n (%) (n=474)* | 305 (64.3) |
| Choroidal neovascularisation, n (%) (n=373)* | |
| Occult | 124 (33.2) |
| Predominantly classic | 74 (19.8) |
| Retinal choroidal anastomosis | 43 (11.5) |
| Minimally classic | 35 (9.4) |
| Retinal pigment epithelium detachment | 30 (8.0) |
| Polypoidal choroidal vasculopathy | 11 (2.9) |
| Other | 56 (15.0) |
| Intraocular pressure, mm Hg (n=280)* | 14.8 (3.1) |
| Diabetes, n (%) | 56 (9.6) |
| Hypertension, n (%) | 212 (36.2) |
| Cardiovascular diseases, n (%) | 96 (16.4) |
Mean (SD) unless stated.
*Data not available for all patients.
AMD, age-related macular degeneration; BCVA, best-corrected visual acuity.