Viral genome and antibodies against herpes viruses in serum from patients with acute retinal necrosis
| Case | PCR ocular | Ocular fluid | PCR ocular fluids (copies/mL) | Symptoms to sampling (days) | Treatment before sampling (days) | PCR serum (copies/mL) | HSV IgM | VZV IgM | HSV1 IgG | HSV2 IgG | VZV IgG | CMV IgG | EBV IgG |
| 1 | VZV | V | 9.4×103 | 48 | 0 | – | – | – | + | – | + | + | + |
| 2 | VZV | V | 8.9×108 | 5 | 0 | + (646) | – | – | + | + | + | + | + |
| 3 | HSV2 | V | 1.8×102 | 270 | 270* | NP | NP | NP | + | + | + | + | NP |
| 4 | HSV1 | V | 1.2×107 | 6 | 2 | – | – | – | + | – | + | + | + |
| 5 | HSV2 | A | positive | 9 | 0 | – | – | – | + | + | + | + | + |
| 6 | HSV1 | V | 5.8×103 | 25 | 0 | – | – | – | + | – | + | – | + |
| 7 | HSV1 | V | 3.6×108 | 7 | 2 | + | – | – | + | – | + | + | + |
| 8 | VZV | A | 2.1×107 | 12 | 1 | + (162) | – | – | – | + | + | – | + |
| 9 | HSV2 | A | 5.7×103 | 8 | 0 | – | – | – | – | + | + | – | + |
| 10 | VZV | A | 1.1×109 | 17 | 0 | – | – | – | – | – | + | + | + |
| 11 | VZV | A | 8.4×106 | 11 | 7 | – | – | – | – | – | + | + | + |
| 12 | VZV | A | 1.5×106 | 12 | 1 | – | – | – | + | + | + | + | + |
| 13 | HSV1 | A | 38 | >20 | 1 | – | – | – | + | – | + | + | + |
Note. +, positive; −, negative.
*Sampling at recurrence.
† first 3 days low dose of acyclovir
A, aqueous;CMV, cytomegalovirus; HSV, herpes simplex virus; NP, not performed;V, vitreous; VZV, varicella zoster virus.