Multivariate analysis of patients with random effects (n=86) | ||
Coefficient (95% CI) | P value | |
Multivariate analysis | ||
ECL~CDE+fluid+operation method+preoperative ECD | ||
CDE | 36.2 (35.6 to 36.9) | 1.319×10– 12* |
Preoperative ECD | 0.193 (0.182 to 0.203) | 0.0056* |
Univariate analysis | ||
Operation method | 106 (98.14 to 113.74) | 0.044* |
Cataract grade I | 376.5 (360.0 to 392.96) | † |
Cataract grade II | 394.67 (377.3 to 415.0) | 0.875 |
Cataract grade III | 515.39 (495 to 535) | 0.305 |
Cataract grade IIII | 298.57 (256.86 to 340.28) | 0.781 |
Surgery time | 17.22 (15.39 to 19.04) | 0.161 |
Preoperative endothelial cell density | 0.21 (0.195 to 0.222) | 0.023* |
Fluid use | 5.545 (5.29 to 5.80) | 0.00163* |
CDE | 35.498 (34.8 to 36.1) | 5.21×10– 13* |
We performed a multivariate analysis with patients with random effects to examine the impact of CDE, fluid use, operation method and preoperative ECD on ECL. We found that CDE is the main contributor to ECL and that preoperative ECD is significant for the amount of ECL. In the univariate model, we found that fluid use and operation method contribute to ECL.
*Statistically significant.
†Cataract grade I serves as a reference to the other cataract grades.
CDE, cumulative dissipated energy; CPS, conventional phaco surgery; ECD, endothelial cell density; ECL, endothelial cell loss; FLACS, femtosecond laser-assisted cataract surgery.