Present case | P16 IHC* | P53 IHC** | In situ hybridisation | β-globin | PCR |
1 | Negative | Positive | Negative | Negative | NA |
2 | Negative | Positive | Negative | Positive | Negative |
3 | Positive | NA | Positive | Positive | HPV 58-positive |
4 | Negative | Positive | Negative | Negative | NA |
* Nuclear and cytoplasmic staining of tumor cells by immunohistochemistry. ** Nuclear staining of tumor cells by immunohistochemistry.
HPV, human papillomavirus; IHC, immunohistochemistry; NA, not available; PCR, polymerase chain reaction.