Table 4

Factors correlated with choroidal MvD area by univariable and multivariable linear mixed analyses in eyes with moderate to advanced glaucoma (n=104)

VariablesUnivariable modelMultivariable model
Coefficient (95% CI)P valueCoefficient (95% CI)P value
Age (year) per 10 years1.55 (−2.95 to 6.05)0.4950.49 (−3.89 to 4.86)0.825
Sex: male−4.17 (−13.82 to 5.47)0.392−8.96 (−17.97 to 0.05)0.051
Race: African American3.14 (−10.33 to 16.6)0.6446.32 (−7.82 to 20.46)0.377
Hypertension−1.60 (−11.47 to 8.27)0.748
Diabetes−14.77 (−22.47 to −7.08)<0.001−4.64 (−14.31 to 5.03)0.342
Axial length, per 1 mm longer1.77 (−1.57 to 5.10)0.294
CCT, per 1 µm thinner0.05 (−0.07 to 0.17)0.383
IOP, per 1 mm Hg higher0.25 (−0.33 to 0.83)0.386
24-2 VF MD, per 1 dB worse0.14 (−0.48 to 0.77)0.6550.17 (−0.51 to 0.84)0.623
Average SSI, per 1 higher0.16 (−0.41 to 0.73)0.583
Smoking intensity, per 10 pack-years3.77 (0.38 to 7.17)0.0300.47 (0.11 to 0.83)0.011
  • The value of MvD area was multiplied by 100 to enhance the readability of the table (unit for the coefficient is 0.01 mm2). Values are shown in mean (95% CI), unless otherwise indicated. Bold text indicates p value with <0.05.

  • CCT, central corneal thickness; IOP, intraocular pressure; MD, mean deviation; MvD, microvasculature dropout; SSI, Signal Strength Index; VF, visual field.