Factors correlated with choroidal MvD area by univariable and multivariable linear mixed analyses in eyes with moderate to advanced glaucoma (n=104)
Variables | Univariable model | Multivariable model | ||
Coefficient (95% CI) | P value | Coefficient (95% CI) | P value | |
Age (year) per 10 years | 1.55 (−2.95 to 6.05) | 0.495 | 0.49 (−3.89 to 4.86) | 0.825 |
Sex: male | −4.17 (−13.82 to 5.47) | 0.392 | −8.96 (−17.97 to 0.05) | 0.051 |
Race: African American | 3.14 (−10.33 to 16.6) | 0.644 | 6.32 (−7.82 to 20.46) | 0.377 |
Hypertension | −1.60 (−11.47 to 8.27) | 0.748 | ||
Diabetes | −14.77 (−22.47 to −7.08) | <0.001 | −4.64 (−14.31 to 5.03) | 0.342 |
Axial length, per 1 mm longer | 1.77 (−1.57 to 5.10) | 0.294 | ||
CCT, per 1 µm thinner | 0.05 (−0.07 to 0.17) | 0.383 | ||
IOP, per 1 mm Hg higher | 0.25 (−0.33 to 0.83) | 0.386 | ||
24-2 VF MD, per 1 dB worse | 0.14 (−0.48 to 0.77) | 0.655 | 0.17 (−0.51 to 0.84) | 0.623 |
Average SSI, per 1 higher | 0.16 (−0.41 to 0.73) | 0.583 | ||
Smoking intensity, per 10 pack-years | 3.77 (0.38 to 7.17) | 0.030 | 0.47 (0.11 to 0.83) | 0.011 |
The value of MvD area was multiplied by 100 to enhance the readability of the table (unit for the coefficient is 0.01 mm2). Values are shown in mean (95% CI), unless otherwise indicated. Bold text indicates p value with <0.05.
CCT, central corneal thickness; IOP, intraocular pressure; MD, mean deviation; MvD, microvasculature dropout; SSI, Signal Strength Index; VF, visual field.