Measurement value of the tissue thickness, vascular density, and visual field sensitivity in controls and patients with glaucoma
| Control (n=96) | Glaucoma (n=90) | P value | Effect size | |
| Tissue thickness (macular) | ||||
| Image quality (arb. unit) | 60.4 (45.3–67.7) | 59.2 (44.6–66.1) | 0.021 | 0.25 |
| mRNFL (μm) | 40.9 (33.4–50.0) | 32.3 (17.5–43.7) | <0.01 | 1.6 |
| mGCL+ (μm) | 63.5 (51.2–72.3) | 57.4 (46.4–67.2) | <0.01 | 1.3 |
| mGCL++ (μm) | 104.4 (88.9–120.2) | 89.6 (67.2–108.2) | <0.01 | 1.8 |
| mRetina (μm) | 270.3 (241.8–295.8) | 257.1 (232.7–283.7) | <0.01 | 1.0 |
| Tissue thickness (disc) | ||||
| Image quality (arb. unit) | 60.4 (42.6–68.2) | 59.2 (45.8–67.6) | 0.036 | 0.23 |
| cpRNFL (μm) | 101.7 (79.5–116.8) | 81.0 (55.1–102.6) | <0.01 | 2.1 |
| cpGCL+ (μm) | 40.6 (31.1–47.1) | 39.3 (26.2–51.0) | 0.052 | 0.28 |
| cpGCL++ (μm) | 141.6 (113.2–160.6) | 120.3 (91.5–142.4) | <0.01 | 1.8 |
| cpRetina (μm) | 280.3 (248.7–311.0) | 262.5 (226.5–290.7) | <0.01 | 1.1 |
| Vascular density (macular) | ||||
| Image quality (arb. unit) | 65.2 (46.7–72.0) | 63.0 (45.8–71.0) | <0.01 | 0.42 |
| Superficial (%) | 33.5 (28.7–36.2) | 31.6 (27.1–35.5) | <0.01 | 1.1 |
| Deep (%) | 42.5 (36.7–51.8) | 41.5 (36.7–45.3) | 0.057 | 0.27 |
| Outer retina (%) | 20.5 (18.4–22.0) | 20.6 (18.5–22.0) | 0.42 | 0.11 |
| Choriocapillaris (%) | 52.4 (49.3–54.6) | 52.2 (41.3–54.3) | 0.58 | 0.13 |
| Vascular density (disc) | ||||
| Image quality (arb. unit) | 65.7 (46.5–73.0) | 64.2 (50.4–71.8) | <0.01 | 0.28 |
| Nerve head (%) | 38.6 (28.1–44.6) | 34.2 (25.5–43.4) | <0.01 | 1.1 |
| Vitreous (%) | 41.4 (34.1–48.4) | 40.5 (32.5–48.4) | 0.049 | 0.26 |
| RPC (%) | 42.1 (33.6–48.0) | 40.1 (32.8–48.0) | <0.01 | 0.55 |
| Choroid disc (%) | 56.2 (39.8–75.1) | 57.5 (39.8–72.8) | 0.22 | 0.15 |
| Visual field | ||||
| Pulsar 24-2 MS (src) | 20.0 (15.8–23.0) | 17.6 (10.8–22.1) | <0.01 | 1.1 |
| Pulsar FP (%) | 1.9 (0–15.8) | 1.5 (0–16.1) | 0.45 | 0.08 |
| Pulsar FN (%) | 0 (0–0) | 0 (0–0) | NA | NA |
| Humphrey 24-2 MS (dB) | 30.1 (26.4–32.6) | 28.1 (23.7–31.2) | <0.01 | 1.1 |
| Humphrey FL (%) | 5.1 (0–16.7) | 5.2 (0–18.1) | 0.78 | 0.017 |
| Humphrey FP (%) | 1.8 (0–9.0) | 2.3 (0–11.8) | 0.36 | 0.18 |
| Humphrey FN (%) | 0.4 (0–3.0) | 2.5 (0–11.8) | <0.01 | 0.71 |
arb. unit, arbitrary unit; cpGCL++, cpRNFL plus cpGCL+; cpGCL+, circumpapillary ganglion cell layer plus inner plexiform layer; cpRetina, circumpapillary retina; cpRNFL, circumpapillary RNFL; FL, fixation loss; FN, false-negative; FP, false-positive; mGCL++, mRNFL plus mGCL+; mGCL+, macular ganglion cell layer plus inner plexiform layer; mRetina, macular retina; mRNFL, macular retinal nerve fibre layer; MS, mean sensitivity; NA, not applicable; RPC, radial peripapillary capillary; src, spatial resolution contrast units.