Table 2

Intraocular pressure before and at 3, 6, 9 and 12 months after brinzolamide (1%)/brimonidine (0.1%) fixed combination prescription

	Group A			Group B			Group C
	IOP (mm Hg)	n	P value*	IOP (mm Hg)	n	P value*	IOP (mm Hg)	n	P value*
Baseline	14.1±3.1	86		15.9±4.0	90		17.2±4.2	123
3M	14.0±2.7	72	0.81	14.4±3.4	80	<0.01	14.0±2.8	102	<0.0001
6M	14.3±3.4	61	0.63	13.8±4.0	74	<0.01	14.1±3.0	97	<0.0001
9M	13.5±3.2	50	0.13	14.1±3.3	68	<0.01	14.8±3.0	82	<0.0001
12M	13.8±2.4	45	0.69	14.5±3.7	58	<0.05	14.9±3.1	66	<0.0001

*Paired t-test.
IOP, intraocular pressure; M, months.