Table 1

Characteristic comparisons of the paired and unpaired cohorts

	FED							PBK
	Paired (group A)		Unpaired				P value	Paired (group A)		Unpaired				P value
	Paired (group A)		B. single		C. double			Paired (group A)		B. single		C. double
	N	%	N	%	N	%		N	%	N	%	N	%
Donor age group*	1	0					<0.01	2	1					<0.01
16–40	1	0	6	1	46	1		2	1	6	1	51	2
41–60	52	11	105	10	621	15		19	7	77	9	456	14
61–75	232	48	440	44	1918	46		109	39	307	37	1351	41
>75 years	203	42	460	45	1567	38		150	54	436	53	1455	44
Endothelial cell density†							<0.01							<0.01
2200–2700	681	70	784	78	2933	71		386	69	663	80	2347	71
>2700	295	30	227	22	1219	29		174	31	163	20	966	29
Donor–recipient sex match							0.04							0.40
Male–female	341	35	336	33	1546	37		171	31	277	34	1038	31
Other combinations	635	65	675	67	2606	63		389	69	549	66	2275	69
Graft type	414	42					0.17	322	58					0.64
PK	414	42	467	46	1889	45		322	58	492	60	1917	58
EK	562	58	544	54	2263	55		238	43	334	40	1396	42
Risk of glaucoma	922	94					0.24	434	78					0.93
No	922	94	957	95	3967	96		434	78	647	78	2587	78
Yes	54	6	54	5	185	4		126	23	179	22	726	22
Total Transplants	976	100	1011	100	4152	100		560	100	826	100	3313	100

*Per donor rather than by transplant.
†When comparing ECD as a continuous variable we found that the difference in ECD for the cohorts was still significant for both FED and PBK (p<0.001)
ECD, endothelial cell density; EK, endothelial keratoplasty; FED, Fuchs endothelial dystrophy ; PBK, pseudophakic bullous keratopathy; PK, penetrating keratoplasty.