Table 1

Demographic and clinical characteristic for study participants

M0M12
Edinburgh
(n=98)
Glasgow
(n=87)
Edinburgh
(n=92)
Glasgow
(n=63)
Age (years, mean±SD)37.17±11.0537.02±9.5839.27±11.1237.29±10.11
Gender (F:M)75:2359:2867:2543:20
Disease duration (days, mean±SD)62.15±36.8859.85±36.28
Visual symptom at onset (n / %)N/AN/A
 Vision loss25/58.14%14/53.85%
 Double vision14/32.56%10/38.46%
 Both4/9.30%2/7.69%
EDSS score (median/IQR)2/1.52/12.5/1.52.5/1
MSFC (median/IQR)0.200/0.6890.167/0.8930.384/0.8810.359/0.741
ON history (n / %)
 No history of ON54/60.67%*39/68.42%†47/58.75%‡27/72.97%§
 Unilateral ON32/35.56%13/22.81%28/35%8/21.62%
 Bilateral ON3/3.37%3/8.77%5/6.25%3/5.41%
  • *Edinburgh site (M0): Total number of 89 participants have ON history available based on self-reported eye questionnaire and clinical records.

  • †Glasgow site (M0): Total number of 55 participants have ON history available based on self-reported eye questionnaire and clinical records.

  • ‡Edinburgh site (M12): Total number of 80 participants have ON history available based on self-reported eye questionnaire and clinical records.

  • §Glasgow site (M12): Total number of 38 participants have ON history available based on self-reported eye questionnaire and clinical records.

  • EDSS, Expanding Disability Status Scale; MSFC, Multiple Sclerosis Functional Composite; ON, Optic Neuritis.