Table 1

Prevalence of ophthalmic findings in the 23 patients with Wolfram syndrome

Study parameterPercentage patients affected
Visual acuity <0.3 logMAR96 (22/23)
RNFL thinning ≤80 μ100 (23/23)
Visual field reduced sensitivity and/or scotoma100 (23/23)
Dyschromatopsia96 (22/23)
Optic nerve pallor96 (22/23)
Optic nerve cup:disc ratio ≥0.439 (9/23)
Afferent pupillary defect65 (15/23)
Nystagmus43 (10/23)
Strabismus43 (10/23)
Cataract22 (5/23)
  • logMAR, log minimum angle resolution; RNFL, retinal nerve fibre layer.