Univariate and multivariate analyses on the risk factors for steroid-refractory patients with idiopathic orbital inflammation (a total of patients, N=159)
| Univariate analysis | Multivariate analysis | |||
| Factor | Applicable steroid-refractory patient no /applicable patient no (%) | P value | OR (95% CI) | P value |
| Patient demography | ||||
| Age (>50) | 27/96 (28) | 0.5 | 0.7 (0.3 to 1.6) | 0.4 |
| Male | 26/89 (29) | 0.8 | ||
| Symptoms (three scores)* | 24/76 (32) | 0.7 | 2.6 (1.0 to 6.4) | 0.05 |
| Onset (>50 days)* | 33/60 (55) | <0.00001 | 8.2 (3.3 to 20) | <0.00001 |
| Initial medium dosage of corticosteroids* | 27/112 (24) | 0.01† | 2.0 (0.9 to 4.8) | 0.1 |
| Anatomical location of lesions | ||||
| Bilaterality | 3/9 (33) | 0.8 | ||
| Myositis | 14/54 (26) | 0.4 | ||
| Dacryoadenitis | 5/28 (18) | 0.3 | ||
| Scleritis and optic perineuritis | 8/23 (35) | 0.6 | ||
| Diffuse (total) | 20/50 (40) | 0.4 | ||
| Diffuse (around eye) | 5/28 (18) | 0.1 | ||
| Diffuse (intramuscle cone) | 9/12 (75) | 0.001 | 6.5 (1.3 to 34) | 0.03 |
| Histopathology | ||||
| Classical | 18/36 (50) | N.D | ||
| Sclerosing | 8/11 (73) | N.D | ||
| Granulomatous | 3/8 (38) | N.D | ||
*χ2 test.
†A significant negative correlation.