Table 1

Infants’ and mothers’ characteristics at study start by treatment group (full analysis set)

Randomised groupP value
AA:DHA (n=84)Control (n=93)
GA (weeks)25.6 (1.5)
25.6 (22.6; 27.9)
25.6 (1.4)
25.9 (22.9; 27.9)
0.79
Female34 (40.5%)43 (46.2%)0.54
Birth weight (g)818 (205)
796 (455; 1345)
795 (196)
770 (425; 1330)
0.45
Birth weight SDS 14−0.66 (1.25)
−0.36 (−5.06; 1.74)
−0.78 (1.16)
−0.50 (−4.06; 1.22)
0.53
Birth length (cm)33.0 (2.7)
33 (27; 39) n=74
33.0 (2.8)
33 (28.5; 41) n=76
0.99
Birth length SDS 14−1.24 (1.61)
−1.02 (−6.76; 1.42) n=74
−1.28 (1.55)
−1.08 (−4.7; 2.89) n=76
0.86
Birth head circumference (cm)23.4 (1.9)
23.4 (18.7; 27.5) n=83
23.3 (1.8)
23.3 (20.2; 27.5) n=91
0.76
Birth head circumference SDS 14−0.61 (0.79)
−0.51 (−2.86; 0.84) n=83
−0.66 (0.78)
−0.63 (−2.50; 1.20) n=91
0.62
Plurality
 Single69 (82.1%)75 (80.6%)
 Twin12 (14.3%)17 (18.3%)
 Triplet3 (3.6%)1 (1.1%)0.89
Centre
 Gothenburg32 (38.1%)33 (35.5%)
 Stockholm25 (29.8%)27 (29.0%)
 Lund27 (32.1%)33 (35.5%)0.89
Morbidities
 NEC5 (6.0%)9 (9.7%)0.53
 PDA49 (58.3%)45 (48.4%)0.24
 Cerebral IVH
  Grade 050 (59.5%)57 (61.3%)
  Grade 114 (16.7%)10 (10.8%)
  Grade 213 (15.5%)12 (12.9%)
  Grade 34 (4.8%)5 (5.4%)
  Grade 43 (3.6%)9 (9.7%)0.42
 BPD48 (57.1%)47 (50.5%)0.47
 Sepsis37 (44.0%)48 (51.6%)0.39
Mother’s age (years)32.2 (5.3)
32.4 (16.2; 41.2)
n=82
31.8 (4.8)
31.1 (22.4; 44)
n=92
0.61
Parity (number of child in order)1.68 (0.88)
1 (1; 5)
n=80
1.63 (0.90)
1 (1; 5)
n=92
0.80
Caesarean section52 (61.9%)55 (59.1%)0.83
Mothers with any medical history42 (50.0%)34 (36.6%)0.098
Mothers with diabetes1 (1.2%)0 (0.0%)0.95
Mothers with hypertension6 (7.1%)13 (14.0%)0.22
  • For categorical variables, n (%) is presented.

  • For continuous variables, mean (SD)/median (minimum; maximum)/n=(unless no. missing) is presented.

  • AA, arachidonic acid; BPD, bronchopulmonary dysplasia; DHA, docosahexaenoic acid; GA, gestational age; IVH, intraventricular haemorrhage; NEC, necrotising enterocolitis; PDA, patent ductus arteriosus; SDS, SD scores.