Secondary outcomes
| Time point 1 (n=38) | Time point 2 (n=38) | P value | |
| BCVA | 62.3±15.1 | 61.6±16.3 | 0.7 |
| CRT | 227.5±47.7 | 233.1±55.5 | 0.4 |
| Year 1 (n=35) | Year 2 (n=35) | P value | |
| Clinical visits | 5.5±1.7 | 3.5±1.2 | 6.1E-07 |
| IVI | 9.1±2.8 | 7.8±3.2 | 0.007 |
Best-corrected ETDRS visual acuity (BCVA) and CRT did not change from time point 1 to time point 2. During the 12 months prior to switch from TNE to OnP number of clinical visits and IVI was higher than during 12 months after switch of protocols. Results are presented as mean±SD.
BCVA, best-corrected visual acuity; CRT, central retinal thickness; ETDRS, Early Treatment Diabetic Retinopathy Study; IVIS, intravitreal injections; OnP, observe-and-plan; TnE, treat-and-extend.