Table 1

Baseline characteristics of eyes with and without OCT features in Best vitelliform macular dystrophy

Pre-VLSolid VLVL with SRFAtrophyPillarFCEIRF
Number of eyes with feature present188587231914
Percentage of total (%)18.98.461.17.424.220.014.7
LogMAR VA (mean, median, range)Feature present0.05, 0.0,
−0.12 to 0.54
0.27, 0.18, 0.10 to 0.900.34, 0.30, –0.12 to 1.000.72, 0.80, 0.54 to 0.880.42, 0.3,
−0.12 to 1.00
0.48, 0.48, 0.00 to 1.000.5, 0.51, 0.1 to 1.00
Feature absent0.37, 0.30, –0.12 to 1.000.31, 0.30, –0.12 to 1.000.26, 0.18, –0.12 to 0.900.27, 0.30,
−0.12 to 0.90
0.27, 0.18, –0.12 to 1.000.28, 0.20, –0.12 to 1.000.28, 0.20, –0.12 to 1.00
P value0.001*0.340.190.001*0.04*0.01*0.003*
% Eyes with VA ≥20/50*Feature present94.488.960.714.352.247.428.6
Feature absent55.860.567.667.166.767.173.1
Age (years) (mean, median, range)Feature present41.3, 35.0, 16 to 8730.4, 27.0, 6 to 6837.5, 34.0, 4 to 8449.0, 57.0, 42 to 6832.8, 31.0, 7 to 6334.0, 32.0, 13 to 6835.6, 28.5, 12 to 60
Feature absent38.3, 36.0, 4 to 8439.5, 36.0, 4 to 8741.0, 38.0, 6 to 8738.1, 34.0, 4 to 8740.8, 39.5, 4 to 8740.1, 37.5, 4 to 8739.5, 37.0, 4 to 87
P value0.310.150.220.0570.04*0.090.24
CST (µm) (mean, median, range)Feature present295.6, 289,
242 to 337
414.8, 397.0,
233 to 570
366.6, 342.0,
177 to 627
227.3, 210.0,
177 to 352
403.0, 391.0,
245 to 627
347.2, 355.0,
73 to 627
363.6, 363.5,
73 to 624
Feature absent358.7, 339.0,
73 to 627
340.5, 316, 73 to 627315.6, 299,
73 to 570
356.2, 329.5,
73 to 627
328.8, 312.5,
73 to 570
346.6, 316.0,
186 to 624
343.8, 316.0,
177 to 627
P value0.001*0.160.018*0.0003*0.003*0.490.32
  • *P value <0.05 considered statistically significant.

  • CST, central subfield thickness; FCE, focal choroidal excavation; IRF, intraretinal fluid; OCT, optical coherence tomography; SRF, subretinal fluid; VA, visual acuity; VL, vitelliform.