Table 3

Multivariable analysis of depression and anxiety scores

Depression scoreAnxiety score
Coefficient (95% CI)P valueCoefficient (95% CI)P value
OSDI (per 10 unit increase)12% (7% to 16%)<0.00112% (7% to 16%)<0.001
Student/unemployed48% (11% to 96%)0.007
House-wife/husband28% (−6% to 76%)0.121
Retired21% (−3% to 52%)0.093
Eye drops per day0.3000.009
None or as required
1–420% (−7% to 54%)0.15336% (5% to 77%)0.022
5+7% (−19% to 41%)0.65157% (17% to 110%)0.003
  • Results are from general linear models, with the log-transformed depression/anxiety scores as the dependent variables. A backward stepwise approach was used to select variables, with the following considered for inclusion: age, gender, ethnicity, education, employment, disease subgroup (OSD/Uveitis), OSDI, steroid use and eye drop frequency. The coefficients were then anti-logged and represent the percentage increase in the anxiety/depression score for the stated category relative to the reference, or for a 10-unit increase in OSDI. Bold p values are significant at p<0.05. N.S.=not selected by the stepwise procedure for inclusion in the final model.

  • OSD, ocular surface disease.