Multivariable analysis of depression and anxiety scores
| Depression score | Anxiety score | |||
| Coefficient (95% CI) | P value | Coefficient (95% CI) | P value | |
| OSDI (per 10 unit increase) | 12% (7% to 16%) | <0.001 | 12% (7% to 16%) | <0.001 |
| Employment | 0.040 | N.S. | ||
| Full/part/self | – | – | – | – |
| Student/unemployed | 48% (11% to 96%) | 0.007 | – | – |
| House-wife/husband | 28% (−6% to 76%) | 0.121 | – | – |
| Retired | 21% (−3% to 52%) | 0.093 | – | – |
| Eye drops per day | 0.300 | 0.009 | ||
| None or as required | – | – | – | – |
| 1–4 | 20% (−7% to 54%) | 0.153 | 36% (5% to 77%) | 0.022 |
| 5+ | 7% (−19% to 41%) | 0.651 | 57% (17% to 110%) | 0.003 |
Results are from general linear models, with the log-transformed depression/anxiety scores as the dependent variables. A backward stepwise approach was used to select variables, with the following considered for inclusion: age, gender, ethnicity, education, employment, disease subgroup (OSD/Uveitis), OSDI, steroid use and eye drop frequency. The coefficients were then anti-logged and represent the percentage increase in the anxiety/depression score for the stated category relative to the reference, or for a 10-unit increase in OSDI. Bold p values are significant at p<0.05. N.S.=not selected by the stepwise procedure for inclusion in the final model.
OSD, ocular surface disease.