Comparative studies showing endophthalmitis rates with and without intracameral antibiotics
| Country | IC antibiotic used | With IC antibiotic | Without IC antibiotic | Reference | ||
| No. of surgeries | POE % (N) | No. of surgeries | POE % (N) | |||
| Sweden | Cefuroxime | 223 156 | 0.045 (100) | 2315 | 0.350 (8) | Lundstorm et al24 |
| 9 countries* | Cefuroxime | 6836 | 0.073 (5) | 6862 | 0.335 (23) | ESCRS study7 |
| France | Cefuroxime | 2289 | 0.044 (1) | 2826 | 1.238 (35) | Barreau et al8 |
| USA | Cefuroxime†/moxifloxacin/vancomycin | 7108 | 0.014 (1) | 2878 | 0.313 (9) | Shorstein et al11 |
| Sweden | Cefuroxime/moxifloxacin | 461 951 | 0.027 (123) | 2804 | 0.39 (11) | Friling et al9 |
| Singapore | Cefazolin | 20 638 | 0.01 (2) | 29 539 | 0.064 (19) | Tan et al25 |
| Japan | Moxifloxacin | 18 794 | 0.01 (3) | 15 958 | 0.05 (8) | Matsuura et al17 |
| Spain | Cefuroxime | 12 868 | 0.039 (5) | 6595 | 0.59 (35) | Rodriguez-Carvacea et al10 |
| Iran | Cefuroxime | 25 920 | 0 (0) | 193 440 | 0.014(28) | Jabbarvand et al12 |
| India | Moxifloxacin | 315 383 | 0.02 (68) | 303 244 | 0.07 (218) | Haripriya et al20 |
| Nepal | Moxifloxacin‡ | 31 340 | 0.025 (8) | 80 643 | 0.144 (116) | Current study |
*Countries include Austria, Belgium, Germany, Italy, Poland, Portugal, Spain, Turkey and UK.
†IC moxifloxacin or IC vancomycin was substituted for cefuroxime in case of suspected allergy to cefuroxime.
‡IC moxifloxacin was used along with subconjunctival gentamycin injection.
ESCRS, European Society of Cataract and Refractive Surgeons; IC, intracameral; POE, postoperative endophthalmitis.