Univariate and multivariate logistic regression analysis of factors that might influence ROP retreatment
| Variable | Univariate analysis | Multivariate analysis | Multivariate analysis laser treatment as first treatment | |||
| P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | |
| Gestational age (weeks) | 0.635 | 0.858 (0.455 to 1.616) | – | – | – | – |
| Birth weight (50 g increment) | 0.062 | 0.815 (0.658 to 1.010) | 0.200 | 0.852 (0.667 to 1.089) | 0.113 | 0.808 (0.621 to 1.052) |
| Sex | 0.838 | 0.938 (0.509 to 1.729 | – | – | – | – |
| APROP | 0.005 | 4.003 (1.537 to 10.424) | 0.119 | 2.733 (0.771 to 9.688) | 0.269 | 2.901 (0.439 to 19.167) |
| Treatment method (anti-VEGF) | <0.001 | 4.686 (1.980 to 11.089) | 0.057 | 3.086 (0.967 to 9.852) | – | – |
| Treatment centre | 0.001 | 1.065 (1.026 to 1.105) | <0.001 | 1.087 (1.043 to 1.134) | <0.001 | 1.085 (1.037 to 1.135) |
| IVH | 0.468 | 1.259 (0.676 to 2.346) | – | – | – | – |
| BPD | 0.806 | 1.173 (0.330 to 4.173) | – | – | – | – |
| NEC | 0.684 | 1.161 (0.564 to 2.391) | – | – | – | – |
| PDA | 0.321 | 0.622 (0.244 to 1.589) | – | – | – | – |
Data presented with p values and ORs and 95% CI.
Covariates with p<0.2 in univariate analysis were entered in a multivariate logistic analysis.
anti-VEGF, antivascular endothelial growth factor; APROP, aggressive posterior retinopathy of prematurity; BPD, bronchopulmonary dysplasia; IVH, intraventricular haemorrhage; NEC, necrotising enterocolitis; PDA, patent ductus arteriosus; ROP, retinopathy of prematurity.