Table 1

Population, Intervention, Comparator, Outcome, Time, Setting (PICOTS) framework

PopulationPatients with amblyopia aged 4–17 years old (±1 year, to either the upper or lower end of that spectrum, but not both), caused by strabismus and/or anisometropia with no other ocular pathologies, mental illnesses, learning disabilities and/or systemic diseases. n>5 participants in the study.
InterventionVision-based treatment conducted in a randomised clinical trial.
ComparatorOther types of vision-based treatments.
OutcomeChange in visual acuity of the amblyopic eye from baseline (logMAR) as the primary outcome.
TimingAny duration.
SettingAny environment (clinical or at home) and any country.