Population, Intervention, Comparator, Outcome, Time, Setting (PICOTS) framework
| PICOTS | Criteria |
| Population | Patients with amblyopia aged 4–17 years old (±1 year, to either the upper or lower end of that spectrum, but not both), caused by strabismus and/or anisometropia with no other ocular pathologies, mental illnesses, learning disabilities and/or systemic diseases. n>5 participants in the study. |
| Intervention | Vision-based treatment conducted in a randomised clinical trial. |
| Comparator | Other types of vision-based treatments. |
| Outcome | Change in visual acuity of the amblyopic eye from baseline (logMAR) as the primary outcome. |
| Timing | Any duration. |
| Setting | Any environment (clinical or at home) and any country. |