Secondary outcome of visual acuity at 9 months postrandomisation
| Group L1 | Group S1 | Group L2 | Group S2 | |
| Low dose, monthly schedule | Standard dose, monthly schedule | Low dose, bimonthly schedule | Standard dose, bimonthly schedule | |
| (n=204) | (n=203) | (n=203) | (n=202) | |
| Distance visual acuity for all eyes: | ||||
| Mean (SD) | 62.4 (16.9) | 63.9 (16.3) | 63.5 (14.2) | 63.4 (15.2) |
| n | 200 | 177 | 182 | 187 |
| Distance visual acuity for primary eye | ||||
| Mean (SD) | 61.8 (17.1) | 63.8 (16.1) | 63.1 (14.2) | 63.1 (15.3) |
| n | 174 | 157 | 167 | 169 |
| Distance visual acuity for fellow eye | ||||
| Mean (SD) | 65.9 (15.7) | 64.5 (17.9) | 68.1 (13.8) | 65.7 (15.2) |
| n | 26 | 20 | 15 | 18 |
| Comparison | Adjusted differences in mean* | 95% CI | ||
| Low dose (L1+L2) vs standard dose (S1 +S2) | −0.96 | −2.08 to 0.17 | ||
| Bimonthly (L2+S2) vs monthly (L1+S1) | 0.13 | −0.99 to 1.25 | ||
| Interaction between dose and schedule | 0.97 | −1.27 to 3.22 | ||
*Adjusted for baseline VA score, each intervention and study centre.
VA, visual acuity.