Demographics of infants and frequency of retinopathy of prematurity (ROP) in the study
| Without ROP frequency (%) (N=733) | With ROP frequency (%) (N=118) | Total frequency (%) (N=851) | P value | |
| Year of birth | <0.001* | |||
| 2013 | 13 (1.77) | 13 (11.02) | 26 (3.06) | |
| 2014 | 95 (12.96) | 30 (25.42) | 125 (14.69) | |
| 2015 | 79 (10.78) | 17 (14.41) | 96 (11.28) | |
| 2016 | 286 (39.02) | 32 (27.12) | 318 (37.37) | |
| 2017 | 218 (29.74) | 21 (17.80) | 239 (28.08) | |
| 2018 | 42 (5.73) | 5 (4.24) | 47 (5.52) | |
| Age (Mean±SD) | 0.006* | |||
| <35 weeks GA | 647 (88.27) | 114 (96.61) | 761 (89.42) | |
| ≥35 weeks GA | 86 (11.73) | 4 (3.39) | 90 (10.58) | |
| Age, corrected | 0.367 | |||
| <35 weeks GA | 248 (33.88) | 35 (29.66) | 283 (33.29) | |
| ≥35 weeks GA | 484 (66.12) | 83 (70.34) | 567 (66.71) | |
| Sex | 0.122 | |||
| Female | 348 (47.48) | 47 (39.83) | 395 (46.42) | |
| Male | 385 (52.52) | 71 (60.17) | 456 (53.58) | |
| Weight (Mean±SD) | <0.001* | |||
| <2000 grams | 612 (83.49) | 114 (96.61) | 726 (85.31) | |
| ≥2000 grams | 121 (16.51) | 4 (3.29) | 125 (14.69) | |
| Initial plan | <0.001* | |||
| Observation | 605 (0.82) | 51 (43.22) | 656 (77.09) | |
| Refer to pedia ophtha | 127 (0.82) | 1 (0.85) | 128 (15.04) | |
| Surgery | 0 | 8 (6.78) | 8 (0.94) | |
| LIO | 0 | 35 (29.66) | 35 (4.11) | |
| Advised prognosis | 0 | 7 (5.93) | 7 (0.82) | |
| Anti-VEGF | 0 | 2 (1.69) | 2 (0.24) | |
| LIO+Anti-VEGF | 1 (0.14) | 14 (11.86) | 15 (1.76) |
*P value <0.05 considered statistically significant.
anti-VEGF, antivascular endothelial growth factor; GA, gestational age; LIO, laser via indirect ophthalmoscopy.