Advanced IIRC grade n=153/189 (81%) | Enucleation* n=134/189 (71%) | Adjuvant chemotherapy* n=68/134 (50%) | ||||
Unadjusted OR | Adjusted OR | Unadjusted OR | Adjusted OR | Unadjusted OR | Adjusted OR | |
Gender | ||||||
Female | 1 | 1 | 1 | 1 | 1 | |
Male | 1.10 | 1.03 (0.46, 2.30) | 1.01 | 1.04 (0.47, 2.30) | 0.68 | 0.50 (0.22, 1.17) |
Ethnicity | ||||||
English/Scottish/Welsh | 1 | 1 | 1 | 1 | 1 | 1 |
Indian/Pakistani/ Bangladeshi | 2.86 | 3.13 (0.62, 16) | 1.86 | 1.40 (0.36, 5.41) | 0.75 | 0.75 (0.22, 2.59) |
Black Caribbean/African | 0.82 | 0.59 (0.09, 3.72) | 0.41 | 0.16 (0.02, 1.18) | 0.28 | 0.35 (0.03, 4.20) |
Mixed/other white or other | 2.05 | 3.92 (0.77, 20) | 1.34 | 0.93 (0.23, 3.76) | 0.37 | 0.37 (0.09, 1.56) |
IMD score (quintiles) | ||||||
1 (most deprived) | 1 | 1 | 1 | 1 | 1 | 1 |
2 | 0.57 | 0.61 (0.17, 2.15) | 1.19 | 1.90 (0.59, 6.17) | 1.13 | 0.94 (0.28, 3.14) |
3 | 0.39 | 0.35 (0.09, 1.37) | 1.11 | 2.55 (0.63, 10) | 1.22 | 1.03 (0.25, 4.28) |
4 | 0.82 | 0.79 (0.19, 3.39) | 1.59 | 1.99 (0.54, 7.37) | 0.92 | 0.55 (0.15, 2.04) |
5 (least deprived) | 0.55 | 0.57 (0.16, 2.07) | 0.99 | 1.19 (0.36, 3.94) | 0.81 | 0.66 (0.20, 2.25) |
Age at diagnosis | ||||||
<1 year | 1 | 1 | 1 | 1 | 1 | 1 |
1 to <2 years | 1.16 | 1.58 (0.59, 4.25) | 1.62 | 1.39 (0.52, 3.74) | 0.52 | 0.66 (0.19, 2.25) |
2 to <3 years | 3.53 | 6.24 (1.50, 26) | 5.12 | 3.58 (0.96, 13) | 0.29 | 0.66 (0.19, 2.30) |
3 to 12 years | 4.5 | 9.57 (2.34, 39) | 6.22 | 4.30 (1.06, 17) | 0.41 | 1.01 (0.31, 3.27) |
Laterality | ||||||
Unilateral | 1 | 1 | 1 | 1 | 1 | 1 |
Bilateral | 1.46 | 3.24 (1.23, 8.57) | 0.52 | 0.48 (0.19, 1.20) | 15 | 16 (4.8, 56) |
Models adjusted for all factors in the table.
Blod values are statistically significant as 95% confidence interval of odds ratio does not include 1.
*Additional adjustment for IIRC groups.
IIRC, International Intraocular Retinoblastoma Classification; IMD, Index of Multiple Deprivation.