Table 1

Distribution of demographic and clinical factors for all cases (n=189), by severity and treatment

	Total n=189		Advanced IIRC groups (D and E) n=153 (81%)		Enucleation n=134 (71%)		Adjuvant chemotherapy n=68
	n	%	n	%	n	%	n	%
Gender
Female	91	48.1	73	48	64	48	36	53
Male	98	51.8	80	52	70	52	32	47
Ethnicity
English/Scottish/Welsh	140	74	110	71.8	98	73.1	54	79.4
Non-English/Scottish/Welsh	48	25.4	42	27.4	35	26.1	14	20.5
Indian/Pakistani/Bangladesh	23	12.1	21	13.7	18	13.4	9	13.2
Black Caribbean/African	8	4.2	6	3.9	4	2.9	1	1.4
Mixed white	11	5.8	9	5.8	8	5.9	1	1.4
Other white	3	1.5	3	1.9	3	2.2	1	1.4
Other	3	1.5	3	1.9	2	1.4	2	2.9
Not known	1	0.5	1	0.6	1	0.7	0	0
IMD score (quintiles)
1 (most deprived)	39	20.6	34	22.2	27	20.1	14	20.5
2	44	23.2	35	22.8	32	23.8	17	25.0
3	29	15.3	21	13.7	20	14.9	11	16.1
4	33	17.4	28	18.3	25	18.6	12	17.6
5 (least deprived)	43	22.7	34	22.2	29	21.6	13	19.1
Not known	1		1		1
Age at diagnosis
<1 year	71	37.5	52	33.9	41	30.5	27	39.7
1 to <2 years	46	24.3	35	22.8	31	23.1	16	23.5
2 to <3 years	32	16.9	29	18.9	28	20.8	10	14.7
3 to <4 years	27	14.2	24	15.6	21	15.6	10	14.7
4 to 12 years	13	6.8	13	8.4	13	9.2	5	7.3
Bilaterality
Unilateral	130	68.7	103	67.3	97	72.3	35	51.4
Bilateral	59	31.2	50	32.6	37	27.6	33	48.5

IIRC, International Intraocular Retinoblastoma Classification; IMD, Index of Multiple Deprivation.