Table 1

Baseline demographic and clinical characteristics

FAS population (n=513)Regular cohort (n=102)Irregular cohort with treatment initiation (n=266)Irregular cohort without treatment initiation (n=60)
Age, years*79.6 (7.9)79.2 (7.6)79.2 (7.7)81.3 (7.1)
Male, n (%)199 (38.8)41 (40.2)103 (38.7)19 (31.7)
Neovascular AMD diagnosis, n (%)
 One eye513 (100.0)102 (100.0)266 (100.0)60 (100.0)
Duration of neovascular AMD, months†0.10.10.20.1
Comorbidities, n (%)
 Diabetes mellitus42 (8.2)7 (6.9)21 (7.9)8 (13.3)
 Hypertension190 (37.0)38 (37.3)106 (39.8)19 (31.7)
 Cardiovascular disease85 (16.6)14 (13.7)47 (17.7)8 (13.3)
CRT, µm (n=458)399.4 (141.9)403.9 (147.8)402.9 (140.1)380.4 (148.4)
CNV on FA, n (%) (n=386)
 Minimally classic34 (8.8)11 (12.5)14 (7.0)6 (13.6)
 Predominantly classic76 (19.7)22 (25.0)29 (14.6)10 (22.7)
 Purely occult130 (33.7)34 (38.6)62 (31.2)15 (34.1)
 Retinal choroidal anastomosis43 (11.1)6 (6.8)25 (12.6)7 (15.9)
 RPE detachment31 (8.0)5 (5.7)23 (11.6)1 (2.3)
 Extrafoveal3 (0.8)1 (1.1)2 (1.0)0
 Subfoveal20 (5.2)2 (2.3)13 (6.5)1 (2.3)
Presence of RPE tear, n (%) (n=386)7 (1.8)04 (2.0)2 (4.5)
Outcomes on SD OCT, n (%) (n=489)
 Presence of subretinal fluid403 (82.4)80 (81.6)213 (83.5)39 (69.6)
 Presence of intraretinal fluid309 (63.2)58 (59.2)159 (62.4)38 (67.9)
 Presence of sub-RPE fluid241 (49.3)47 (48.0)134 (52.5)28 (50.0)
 Pigment epithelium detachment309 (63.2)52 (53.1)175 (68.6)31 (55.4)
 Suspicion for RAP59 (12.1)13 (13.3)31 (12.2)7 (12.5)
 PCV31 (6.3)6 (6.1)14 (5.5)5 (8.9)
  • *Mean (SD).

  • †Median.

  • AMD, age-related macular degeneration; CNV, choroidal neovascularisation; CRT, central retinal thickness; FA, fluorescein angiography; FAS, full analysis set; PCV, polypoidal choroidal vasculopathy; RAP, retinal angiomatous proliferation; RPE, retinal pigment epithelium; SD OCT, spectral domain optical coherence tomography.