RT Journal Article
SR Electronic
T1 Metagenomics in ophthalmology: current findings and future prospectives
JF BMJ Open Ophthalmology
JO BMJ Open Ophth
FD BMJ Publishing Group Ltd
SP e000248
DO 10.1136/bmjophth-2018-000248
VO 4
IS 1
A1 Davide Borroni
A1 Vito Romano
A1 Stephen B Kaye
A1 Tobi Somerville
A1 Luca Napoli
A1 Adriano Fasolo
A1 Paola Gallon
A1 Diego Ponzin
A1 Alfonso Esposito
A1 Stefano Ferrari
YR 2019
UL http://bmjophth.bmj.com/content/4/1/e000248.abstract
AB Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a ‘hypothesis-free’ approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases.