PT  - JOURNAL ARTICLE
AU  - Davide Borroni
AU  - Vito Romano
AU  - Stephen B Kaye
AU  - Tobi Somerville
AU  - Luca Napoli
AU  - Adriano Fasolo
AU  - Paola Gallon
AU  - Diego Ponzin
AU  - Alfonso Esposito
AU  - Stefano Ferrari
TI  - Metagenomics in ophthalmology: current findings and future prospectives
AID  - 10.1136/bmjophth-2018-000248
DP  - 2019 Jun 01
TA  - BMJ Open Ophthalmology
PG  - e000248
VI  - 4
IP  - 1
4099  - http://bmjophth.bmj.com/content/4/1/e000248.short
4100  - http://bmjophth.bmj.com/content/4/1/e000248.full
SO  - BMJ Open Ophth2019 Jun 01; 4
AB  - Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a ‘hypothesis-free’ approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases.