%0 Journal Article %A Davide Borroni %A Vito Romano %A Stephen B Kaye %A Tobi Somerville %A Luca Napoli %A Adriano Fasolo %A Paola Gallon %A Diego Ponzin %A Alfonso Esposito %A Stefano Ferrari %T Metagenomics in ophthalmology: current findings and future prospectives %D 2019 %R 10.1136/bmjophth-2018-000248 %J BMJ Open Ophthalmology %P e000248 %V 4 %N 1 %X Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a ‘hypothesis-free’ approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases. %U https://bmjophth.bmj.com/content/bmjophth/4/1/e000248.full.pdf