PT  - JOURNAL ARTICLE
AU  - Osmel P Alvarez
AU  - Mike Zein
AU  - Anat Galor
AU  - Carol L Karp
TI  - Management of ocular surface squamous neoplasia: Bowman Club Lecture 2021
AID  - 10.1136/bmjophth-2021-000842
DP  - 2021 Jul 01
TA  - BMJ Open Ophthalmology
PG  - e000842
VI  - 6
IP  - 1
4099  - http://bmjophth.bmj.com/content/6/1/e000842.short
4100  - http://bmjophth.bmj.com/content/6/1/e000842.full
SO  - BMJ Open Ophth2021 Jul 01; 6
AB  - The gold-standard treatment for ocular surface squamous neoplasia (OSSN) has traditionally been surgical excision with wide margins and a no-touch technique. However, surgery may be associated with several unfavourable sequelae, as well as significant recurrence rates if margins are positive. In recent years, topical chemotherapy with 5-fluorouracil, interferon α−2b and mitomycin C have emerged as valuable agents capable of effectively treating OSSN with varying adverse effects. These medical treatment options usually present additional costs to the patient but can allow patients to avoid surgery with fewer long-term effects. Anterior segment high-resolution optical coherence tomography is an excellent tool for diagnosing and monitoring OSSN and can be a useful aid for both surgical and medical treatments of OSSN.No data are available. Not applicable.