You are here

  • Home
  • Archive
  • Volume 5, Issue 1
  • Assessing full thickness oral mucosal grafting: complications and postoperative outcomes in a broad collective of patients

Article Text

Article menu

Download PDFPDF

XML
Original research
Assessing full thickness oral mucosal grafting: complications and postoperative outcomes in a broad collective of patients
  1. Daniel Pilger,
  2. Christoph von Sonnleithner,
  3. Eckart Bertelmann
  1. Department of Ophthalmology, Charité – Universitätsmedizin Berlin, Berlin, Germany
  1. Correspondence to Prof. Eckart Bertelmann; eckart.bertelmann{at}charite.de

Abstract

Background Conjunctival defects can be repaired with several mucosal tissues. The simplicity of harvesting oral mucosa and its wide availability makes it the preferred graft tissue for all indications requiring mucosal grafting. Through analysing the postsurgical outcomes and rate of revisions, this study explores the suitability of oral mucosa grafts, depending on the initial diagnosis.

Methods We reviewed all the files of patients with a history of oral mucosal graft surgery, performed at our clinic between 2012 and 2018, focusing on complications and revision rates.

Results In total, we analysed 173 oral mucosa grafts in 131 patients. The most common initial diagnosis was tumour resection, followed by surgical complications, postenucleation socket syndrome, trauma and ocular surface disorders. Complication and revision rates depended highly on the initial diagnosis. Revision rates were highest if the initial diagnosis included ocular surface disorders or chemical trauma.

Conclusions Oral mucosa grafting (OMG) is the most effective treatment for a wide range of ocular conditions involving conjunctival defects. Conjunctival defects that result from trauma or cicatricial surface diseases seem less suitable for OMG and may benefit from alternative graft tissue or treatment options.

  • eye Lids
  • orbit
  • treatment surgery
  • trauma
  • ocular surface
http://creativecommons.org/licenses/by-nc/4.0/

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.1136/bmjophth-2019-000337

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • DP and CvS contributed equally.

    • Contributors DP: data collection, concept, implementation, data analysis and interpretation,writing manuscript, submission of the manuscript. CvS: implementation, data collection, interpretation and critical review of the manuscript. EB: implementation, concept, interpretation and critical review of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Not required.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Data availability statement Data are available upon request